Evidence map›Paper›PMID 33578416›Full record

ReviewAdvances in nutrition (Bethesda, Md.)2021

Functional Meat Products as Oxidative Stress Modulators: A Review.

Adrián Macho-González, Sara Bastida, Alba Garcimartín, María Elvira López-Oliva, Pilar González, Juana Benedí, María José González-Muñoz, Francisco J Sánchez-Muniz

Open access · greenAbstract readReview
In one paragraph

Review in Advances in nutrition (Bethesda, Md.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Boosting nutritional value: the role of iron fortification in meat and meat products.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025
    Review
  5. Article
  6. Article
  7. Spicing Up Meat Preservation:Foods (Basel, Switzerland) · 2024
    Review
  8. Article
  9. Strategies for Healthier Meat Foods: An Overview.Preventive nutrition and food science · 2024
    Review
  10. Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Adrián Macho-GonzálezNutrition and Food Science Department (Nutrition), Pharmacy School, Complutense University of Madrid, Madrid, Spain.
Sara BastidaNutrition and Food Science Department (Nutrition), Pharmacy School, Complutense University of Madrid, Madrid, Spain.
Alba GarcimartínPharmacology, Pharmacognosy and Botany Department, Pharmacy School, Complutense University of Madrid, Madrid, Spain.
María Elvira López-OlivaDepartmental Section of Physiology, Pharmacy School, Complutense University of Madrid, Madrid, Spain.
Pilar GonzálezPharmacology, Pharmacognosy and Botany Department, Pharmacy School, Complutense University of Madrid, Madrid, Spain.
Juana BenedíPharmacology, Pharmacognosy and Botany Department, Pharmacy School, Complutense University of Madrid, Madrid, Spain.
María José González-MuñozBiomedical Sciences Department, Toxicology Teaching Unit, Pharmacy School, Alcala University, Alcalá de Henares, Spain.
Francisco J Sánchez-MunizNutrition and Food Science Department (Nutrition), Pharmacy School, Complutense University of Madrid, Madrid, Spain.ORCID 0000-0002-2660-5126
Universidad Complutense de Madrid · ESUniversidad de Alcalá · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High meat consumption has been associated with increased oxidative stress mainly due to the generation of oxidized compounds in the body, such as malondialdehyde, 4-hydroxy-nonenal, oxysterols, or protein carbonyls, which can induce oxidative damage. Meat products are excellent matrices for introducing different bioactive compounds, to obtain functional meat products aimed at minimizing the pro-oxidant effects associated with high meat consumption. Therefore, this review aims to summarize the concept and preparation of healthy and functional meat, which could benefit antioxidant status. Likewise, the key strategies regarding meat production and storage as well as ingredients used (e.g., minerals, polyphenols, fatty acids, walnuts) for developing these functional meats are detailed. Although most effort has been made to reduce the oxidation status of meat, newly emerging approaches also aim to improve the oxidation status of consumers of meat products. Thus, we will delve into the relation between functional meats and their health effects on consumers. In this review, animal trials and intervention studies are discussed, ascertaining the extent of functional meat products' properties (e.g., neutralizing reactive oxygen species formation and increasing the antioxidant response). The effects of functional meat products in the frame of diet-gene interactions are analyzed to 1) discover target subjects that would benefit from their consumption, and 2) understand the molecular mechanisms that ensure precision in the prevention and treatment of diseases, where high oxidative stress takes place. Long-term intervention-controlled studies, testing different types and amounts of functional meat, are also necessary to ascertain their positive impact on degenerative diseases.

Indexed as

Meat ProductsAnimalsAntioxidantsHumansMalondialdehydeMeatOxidative StressAntioxidantsMalondialdehydeanimal trialsantioxidant mechanismsbioactive ingredientsfunctional meatintervention studiesmetabolismoxidation statusprecision diet

Identifiers

PMID33578416
PMCPMC8321872
OpenAlexW3128460398

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.