Evidence map›Paper›PMID 33578038›Full record

ArticleMolecular therapy : the journal of the American Society of Gene Therapy2021

RETRACTED: Tumor cell-secreted exosomal miR-22-3p inhibits transgelin and induces vascular abnormalization to promote tumor budding.

Yaju Feng, Lumeng Wang, Ting Wang, Ying Li, Qingqing Xun, Renya Zhang, Lin Liu, Lei Li, Wei Wang, Yixuan Tian and 6 more

RetractedOpen access · bronzeAbstract readRetracted Publication
In one paragraph

Article in Molecular therapy : the journal of the American Society of Gene Therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Potential biological roles of exosomal non-coding RNAs in breast cancer.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Yaju FengDepartment of Pathology, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining 272029, Shandong, China; State Key Laboratory of Medicinal Chemical Biology and College of Pharmacy, Nankai University, Tianjin 300350, China; Tianjin Key Laboratory of Early Druggability Evaluation of Innovative Drugs and Tianjin Key Laboratory of Molecular Drug Research, Tianjin International Joint Academy of Biomedicine, Tianjin 300457, China.
Lumeng WangState Key Laboratory of Medicinal Chemical Biology and College of Pharmacy, Nankai University, Tianjin 300350, China; Tianjin Key Laboratory of Early Druggability Evaluation of Innovative Drugs and Tianjin Key Laboratory of Molecular Drug Research, Tianjin International Joint Academy of Biomedicine, Tianjin 300457, China.
Ting WangDepartment of Pathology, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining 272029, Shandong, China.
Ying LiDepartment of Pathology, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining 272029, Shandong, China.
Qingqing XunDepartment of Pathology, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining 272029, Shandong, China; School of Clinical Medicine, Jining Medical University, Jining 272029, Shangdong, China.
Renya ZhangDepartment of Pathology, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining 272029, Shandong, China.
Lin LiuHealth Management Center, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining 272029, Shandong, China.
Lei LiDepartment of Pathology, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining 272029, Shandong, China.
Wei WangDepartment of Pathology, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining 272029, Shandong, China.
Yixuan TianState Key Laboratory of Medicinal Chemical Biology and College of Pharmacy, Nankai University, Tianjin 300350, China; Tianjin Key Laboratory of Early Druggability Evaluation of Innovative Drugs and Tianjin Key Laboratory of Molecular Drug Research, Tianjin International Joint Academy of Biomedicine, Tianjin 300457, China.
Lili YangDepartment of Pathology, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining 272029, Shandong, China.
Xiao ZhiDepartment of Pathology, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining 272029, Shandong, China.
Bijiao ZhouState Key Laboratory of Medicinal Chemical Biology and College of Pharmacy, Nankai University, Tianjin 300350, China; Tianjin Key Laboratory of Early Druggability Evaluation of Innovative Drugs and Tianjin Key Laboratory of Molecular Drug Research, Tianjin International Joint Academy of Biomedicine, Tianjin 300457, China.
Xin ChenState Key Laboratory of Medicinal Chemical Biology and College of Pharmacy, Nankai University, Tianjin 300350, China; Tianjin Key Laboratory of Early Druggability Evaluation of Innovative Drugs and Tianjin Key Laboratory of Molecular Drug Research, Tianjin International Joint Academy of Biomedicine, Tianjin 300457, China.
Tao SunState Key Laboratory of Medicinal Chemical Biology and College of Pharmacy, Nankai University, Tianjin 300350, China; Tianjin Key Laboratory of Early Druggability Evaluation of Innovative Drugs and Tianjin Key Laboratory of Molecular Drug Research, Tianjin International Joint Academy of Biomedicine, Tianjin 300457, China. Electronic address: sunrockmia@hotmail.com.
Yanrong LiuDepartment of Pathology, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining 272029, Shandong, China. Electronic address: liuyanrong1984@163.com.
Affiliated Hospital of Jining Medical University · CNTianjin International Joint Academy of Biomedicine · CNNankai University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the editor-in-chief. The editor-in-chief was informed of evidence for image duplication in identical or altered fashion in Figures 3A and 8D, as well as undisclosed reuse of an image in Figure 5B from a previous article in Cell Death & Disease (https://doi.org/10.1038/s41419-018-0902-5), in a PubPeer thread: https://pubpeer.com/publications/F5B591481C516F4CE42C7925AC48E9. Image analysis performed by the journal's editorial office confirmed these findings. This reuse (and in part misrepresentation) of data without appropriate attribution represents a severe abuse of the scientific publishing system.

Indexed as

Gene Expression Regulation, NeoplasticRNA InterferenceAnimalsBreast NeoplasmsCell Line, TumorCell MovementCytoskeletonDisease Models, AnimalEndothelial CellsExosomesFemaleHeterograftsHumansMiceMicrofilament ProteinsMicroRNAsMicrofilament ProteinsMicroRNAsMIRN22 microRNA, humanMuscle Proteinstransgelinbreast cancerexosomesmiR-22-3ptransgelintumor budding

Identifiers

PMID33578038
PMCPMC8178443
OpenAlexW3126965852

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.