ReviewFASEB journal : official publication of the Federation of American Societies for Experimental Biology2021
COVID-19: Current knowledge in clinical features, immunological responses, and vaccine development.
Review in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Convalescent Plasma for the Prevention and Treatment of COVID-19: A Systematic Review and Quantitative Analysis.JMIR public health and surveillance · 2021Pooled it
- Efficacy of Integrated Traditional Chinese and Western Medicine for Treating COVID-19: A Systematic Review and Meta-Analysis of RCTs.Frontiers in public health · 2021Pooled it
- The Way of SARS-CoV-2 Pneumonia-An Early-Pandemic Review of the Key Manifestations and Severity.Journal of clinical medicine · 2025Review
- Short-term risk of psychiatric adverse events following COVID-19 vaccination: nationwide self-controlled case series study.BJPsych open · 2025Article
- Long COVID-19 Enigma: Unmasking the Role of Distinctive Personality Profiles as Risk Factors.Journal of clinical medicine · 2024Article
- Genetic Predisposition to SARS-CoV-2 Infection: Cytokine Polymorphism and Disease Transmission within Households.Biology · 2023Article
- Adenoviral-vectored next-generation respiratory mucosal vaccines against COVID-19.Current opinion in virology · 2023Review
- COVID-19 infection in patients on long-term home parenteral nutrition for chronic intestinal failure.Clinical nutrition ESPEN · 2023Article
- Reverse transcription-loop-mediated isothermal amplification (RT-LAMP) assay as a rapid molecular diagnostic tool for COVID-19 in healthcare workers.Journal of clinical virology plus · 2023Article
- The Top 100 Most Cited Neurosurgical Articles on COVID-19: A Bibliometric Analysis.World neurosurgery · 2023Review
- Pediatric COVID-19 Involving Complicated Sinusitis With Intracranial Extension and Lemierre Syndrome: A Case Report.Cureus · 2023Article
- Statin therapy may protect against acute kidney injury in patients hospitalized for interstitial SARS-CoV2 pneumonia.Nutrition, metabolism, and cardiovascular diseases : NMCD · 2023Observational
- Design of multi-epitope vaccine candidate against Brucella type IV secretion system (T4SS).PloS one · 2023Article
- A comprehensive study of Ecuadorian adult patients with a mild and moderate presentation of COViD-19.PloS one · 2023Article
- CD4 + Count: a Variable to Be Considered to Prioritize COVID-19 Vaccination in PLHIV.Current pharmacology reports · 2023Review
- Article
- Human induced pluripotent stem cell-derived salivary gland organoids model SARS-CoV-2 infection and replication.Nature cell biology · 2022Article
- A Systematic Review of COVID-19 Vaccine Antibody Responses in People With HIV.Open forum infectious diseases · 2022Review
- Co-infection associated with SARS-CoV-2 and their management.Future science OA · 2022Review
- SARS-CoV-2 infection in multiple sclerosis patients: interaction with treatments, adjuvant therapies, and vaccines against COVID-19.Journal of neurology · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
The COVID-19 pandemic has unfolded to be the most challenging global health crisis in a century. In 11 months since its first emergence, according to WHO, the causative infectious agent SARS-CoV-2 has infected more than 100 million people and claimed more than 2.15 million lives worldwide. Moreover, the world has raced to understand the virus and natural immunity and to develop vaccines. Thus, within a short 11 months a number of highly promising COVID-19 vaccines were developed at an unprecedented speed and are now being deployed via emergency use authorization for immunization. Although a considerable number of review contributions are being published, all of them attempt to capture only a specific aspect of COVID-19 or its therapeutic approaches based on ever-expanding information. Here, we provide a comprehensive overview to conceptually thread together the latest information on global epidemiology and mitigation strategies, clinical features, viral pathogenesis and immune responses, and the current state of vaccine development.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.