ReviewNeuropsychology review2021
Decision-Making Competence in Patients with Alzheimer's Disease: A Review of the Literature.
Review in Neuropsychology review, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Measures of decision-making ability and functional outcomes in older adults: results from a scoping review in the ARMCADA study.Frontiers in psychology · 2025Pooled it
- Attitudes of older adults toward active euthanasia in advanced Alzheimer's disease.Journal of Alzheimer's disease : JAD · 2026Article
- A scoping review of emotion and non-cognitive measures of decision-making ability in older adults by the ARMCADA study.Frontiers in public health · 2026Article
- Noisy Memory Generates Value in Changing Environments.Adaptive behavior · 2025Article
- Thinking About It All Together: A Descriptive Analysis to Understand Comorbidities in People Living With Dementia.Health science reports · 2025Article
- Unvalidated efficacy and significant risks hinder clinical use of deep cervical lymphatic-venous anastomosis for Alzheimer's disease.Frontiers in aging neuroscience · 2025Review
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- Article
- The Impact of Episodic Memory on Decision-Making in Aging: Scenarios from Everyday Life Situations.Brain sciences · 2024Article
- Phishing vulnerability compounded by older age, apolipoprotein E e4 genotype, and lower cognition.PNAS nexus · 2024Article
- Study protocol for the development and validation of a clinical prediction tool to estimate the risk of 1-year mortality among hospitalized patients with dementia.Diagnostic and prognostic research · 2024Article
- Cognitive, Emotional, and Daily Functioning Domains Involved in Decision-Making among Patients with Mild Cognitive Impairment: A Systematic Review.Brain sciences · 2024Review
- Mesenchymal Stem Cell-Derived Extracellular Vesicles: An Emerging Diagnostic and Therapeutic Biomolecules for Neurodegenerative Disabilities.Biomolecules · 2023Review
- Ginsenoside Rg1 in neurological diseases: From bench to bedside.Acta pharmacologica Sinica · 2023Review
- Mild Cognitive Impairment is Associated with Poorer Everyday Decision Making.Journal of Alzheimer's disease : JAD · 2023Article
- Healthcare decision-making capacity in old age: A qualitative study.Frontiers in psychology · 2022Article
- Aducanumab: Appropriate Use Recommendations Update.The journal of prevention of Alzheimer's disease · 2022Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Decision-making competence (DMC) appears to be influenced by the congruency between the characteristics of the individual, the task and the context. Indeed, the ability to make decisions seems to be highly sensitive to cognitive changes as observed, in particular, in the healthy elderly. Few studies have investigated these relations in pathological ageing. In this review, we focus on DMC in patients with Alzheimer's disease (AD) and the links its impairment could have with deficits in episodic memory, working memory, and executive functions. Decision-making under risk and under ambiguity appears to be impaired early in the progress of AD, with the deficit being greater during the later stages of the disease. In addition, some studies suggest that the impairment of DMC is exacerbated by deficits in other cognitive functions, in particular working memory and executive functions. This degradation in the ability to make decisions seriously affects the quality of life of patients and their relatives, since they frequently face important decisions, especially concerning healthcare, finance or accommodation. Thus, the growing incapacity to decide for themselves increases patients' and caregivers' stress and burden. The challenge for future studies is to determine how best to help patients and their families in the decisional process.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.