ArticlePlant physiology2021
TCP transcription factors suppress cotyledon trichomes by impeding a cell differentiation-regulating complex.
Article in Plant physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 54 citations in OpenAlex.
- Comprehensive transcriptomic analysis of BjGL1-knockout Brassica juncea: novel insights into leaf trichome formation.Transgenic research · 2026Article
- Decoding the landscape of cell-type-specific co-expressed transcription factors in soybean.Nature plants · 2026Article
- A group of TCP transcription factors is a missing link in strigolactone signaling.Journal of integrative plant biology · 2026Article
- VrMYB90 negatively regulates proanthocyanidin biosynthesis by repressing VrANR in mung bean (Vigna radiata L.).Planta · 2025Article
- The CIN-TCP transcription factors regulate endocycle progression and pavement cell size by promoting cell wall pectin degradation.Nature communications · 2025Article
- Wo interacts with SlTCP25 to regulate type I trichome branching in tomato.Horticulture research · 2025Article
- Flavones enrich rhizosphere Pseudomonas to enhance nitrogen utilization and secondary root growth in Populus.Nature communications · 2025Article
- Genome-Wide Identification and Expression Analysis ofInternational journal of molecular sciences · 2025Article
- Comprehensive analysis of PLATZ family genes and their responses to abiotic stresses in Barley.BMC plant biology · 2024Article
- Arabidopsis transcription factor TCP4 controls the identity of the apical gynoecium.The Plant cell · 2024Article
- Rice transcriptional repressor OsTIE1 controls anther dehiscence and male sterility by regulating JA biosynthesis.The Plant cell · 2024Article
- BrrTCP4b interacts with BrrTTG1 to suppress the development of trichomes inPlant diversity · 2024Article
- Sea-ATI unravels novel vocabularies of plant active cistrome.Nucleic acids research · 2023Article
- Arabidopsis TCP4 transcription factor inhibits high temperature-induced homeotic conversion of ovules.Nature communications · 2023Article
- The TaTCP4/10-B1 cascade regulates awn elongation in wheat (Triticum aestivum L.).Plant communications · 2023Article
- Article
- Arabidopsis transcription factor TCP4 represses chlorophyll biosynthesis to prevent petal greening.Plant communications · 2022Article
- Genome-wide analysis of citrus TCP transcription factors and their responses to abiotic stresses.BMC plant biology · 2022Article
- Article
- Chromosome-Level Genome Assembly forFrontiers in plant science · 2022Article
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Trichomes are specialized epidermal cells that act as barriers against biotic and abiotic stresses. Although the formation of trichomes on hairy organs is well studied, the molecular mechanisms of trichome inhibition on smooth organs are still largely unknown. Here, we demonstrate that the CINCINNATA (CIN)-like TEOSINTE BRANCHED1/CYCLOIDEA/PCF (TCP) transcription factors inhibit the formation of trichomes on cotyledons in Arabidopsis (Arabidopsis thaliana). The tcp2/3/4/5/10/13/17 septuple mutant produces cotyledons with ectopic trichomes on the adaxial sides. The expression patterns of TCP genes are developmentally regulated during cotyledon development. TCP proteins directly interact with GLABRA3 (GL3), a key component of the MYB transcription factor/basic helix-loop-helix domain protein/WD40-repeat proteins (MYB-bHLH-WD40, MBW) complex essential for trichome formation, to interfere with the transactivation activity of the MBW complex in cotyledons. TCPs also disrupt the MBW complex-R3 MYB negative feedback loop by directly promoting the expression of R3 MYB genes, which enhance the repression of the MBW complex. Our findings reveal a molecular framework in which TCPs suppress trichome formation on adaxial sides of cotyledons by repressing the activity of the MBW complex at the protein level and the transcripts of R3 MYB genes at the transcriptional level.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.