Evidence map›Paper›PMID 33576569›Full record

ArticleJournal of biophotonics2021

LightBox: A multiwell plate illumination system for photoactive molecule characterization.

A D Bounds, R D Bailey, C T Adams, D C Callaghan, J M Girkin

Abstract read
In one paragraph

Article in Journal of biophotonics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

A D BoundsCentre for Advanced Instrumentation, Department of Physics, Durham University, Durham, DH1 3LE, UK.ORCID 0000-0002-5067-8691
R D BaileyCentre for Advanced Instrumentation, Department of Physics, Durham University, Durham, DH1 3LE, UK.
C T AdamsDepartment of Biosciences, Durham University, Durham, DH1 3LE, UK.
D C CallaghanDepartment of Biosciences, Durham University, Durham, DH1 3LE, UK.
J M GirkinCentre for Advanced Instrumentation, Department of Physics, Durham University, Durham, DH1 3LE, UK.ORCID 0000-0003-2568-3576

Funding

Medical Research Council Confidence in Concept award
6 · The paper itself

Abstract

Multiwell plates (MWPs) are the workhorses of the life sciences. However, biophotonics research with MWPs is limited, in part due to the lack of equipment suitable for photo-irradiation of photoactive molecules in a MWP-suitable, high-throughput manner, either commercially or through open-source MWP systems. Here we present "LightBox", a calibrated controllable MWP illumination system with broad applications including screening of photoactive molecules and characterization of photocatalytic chemicals. LightBox is a high intensity, accurately controllable, uniform illumination system designed for MWPs with electronics and a control unit that provides a simple and intuitive interface. LightBox can reach intensities of 0.23 mW/mm

Indexed as

Lightingbio-instrumentationbio-photonicsphotoactive moleculesphotodynamic therapy

Identifiers

PMID33576569
PMCPMC11475348

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.