ArticleAngewandte Chemie (International ed. in English)2021
Enantioselective Alkoxycyclization of 1,6-Enynes with Gold(I)-Cavitands: Total Synthesis of Mafaicheenamine C.
Article in Angewandte Chemie (International ed. in English), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Gold catalysis toward the synthesis of natural products: a review.RSC advances · 2026Review
- Enantioselective cyclization of bromoenynes: mechanistic understanding of gold(i)-catalyzed alkoxycyclizations.Chemical science · 2026Article
- Lewis acid-promoted intramolecular cyclization ofRSC advances · 2025Article
- Computational Study of Alkyne-Acid Cycloisomerization in Gold-Functionalized Resorcinarene Cavitand.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- Practical Synthesis of Chiral Ferrocenenylphosphino-Gold(I) Catalysts and NEST Analysis of the Enantioinduction.ACS catalysis · 2025Article
- The Versatile Applications of Calix[4]resorcinarene-Based Cavitands.Molecules (Basel, Switzerland) · 2024Review
- Hydration of Propargyl Esters Catalyzed by Gold(I) Complexes with Phosphoramidite Calix[4]pyrrole Cavitands as Ligands.Inorganic chemistry · 2023Article
- Hydrogen-Bonded Matched Ion Pair Gold(I) Catalysis.ACS catalysis · 2023Article
- Enantioselective Catalysis with Pyrrolidinyl Gold(I) Complexes: DFT and NEST Analysis of the Chiral Binding Pocket.JACS Au · 2023Article
- H-Bonded Counterion-Directed Catalysis: Enantioselective Gold(I)-Catalyzed Addition to 2-Alkynyl Enones as a Case Study.European journal of organic chemistry · 2022Article
- H-Bonded Counterion-Directed Enantioselective Au(I) Catalysis.Journal of the American Chemical Society · 2022Article
- Diametric calix[6]arene-based phosphine gold(I) cavitands.Beilstein journal of organic chemistry · 2022Article
- New-Generation Ligand Design for the Gold-Catalyzed Asymmetric Activation of Alkynes.ChemPlusChem · 2021Review
- Enantioselective Alkoxycyclization of 1,6-Enynes with Gold(I)-Cavitands: Total Synthesis of Mafaicheenamine C.Angewandte Chemie (International ed. in English) · 2021Article
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5 authors.
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Abstract
Chiral gold(I)-cavitand complexes have been developed for the enantioselective alkoxycyclization of 1,6-enynes. This enantioselective cyclization has been applied for the first total synthesis of carbazole alkaloid (+)-mafaicheenamine C and its enantiomer, establishing its configuration as R. The cavity effect was also evaluated in the cycloisomerization of dienynes. A combination of experiments and theoretical studies demonstrates that the cavity of the gold(I) complexes forces the enynes to adopt constrained conformations, which results in the high observed regio- and stereoselectivities.
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