Evidence map›Paper›PMID 33576177›Full record

SynthesisESC heart failure2021

Sarcopenia in heart failure: a systematic review and meta-analysis.

Yan Zhang, Jia Zhang, Wenqing Ni, Xueli Yuan, Hongmin Zhang, Ping Li, Jian Xu, Zhiguang Zhao

Registry-linked trialOpen access · goldAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in ESC heart failure, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06298825 (Effect of Sarcopenia on Prognosis of Patients With Acute Decompensated Heart Failure), which is not on this map. Cited by 112 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
112citing papers in PubMed, 11 pooled it
13.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06298825 unknown statusnot on this mapstarted 2024, after this paper: background citation

Effect of Sarcopenia on Prognosis of Patients With Acute Decompensated Heart Failure: a Prospective, Multi-center, Observational Cohort Study

TypeobservationalSponsorGuangdong Provincial People's HospitalRan2024 to 2026Enrolled500ConditionsAcute Decompensated Heart Failure
3 · Its place in the literature

Who cites it

112 citing papers in PubMed, 11 syntheses or guidelines pooled it, 187 citations in OpenAlex.

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  19. A cardiovascular-motor axis framework for perfusion-mediated motor impairment.International journal of cardiology. Heart & vasculature · 2026
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52 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yan ZhangDepartment of Elderly Health Management, Shenzhen Center for Chronic Disease Control, Shenzhen, Guangdong, 518020, China.ORCID 0000-0002-4407-6686
Jia ZhangDepartment of Elderly Health Management, Shenzhen Center for Chronic Disease Control, Shenzhen, Guangdong, 518020, China.
Wenqing NiDepartment of Elderly Health Management, Shenzhen Center for Chronic Disease Control, Shenzhen, Guangdong, 518020, China.
Xueli YuanDepartment of Elderly Health Management, Shenzhen Center for Chronic Disease Control, Shenzhen, Guangdong, 518020, China.
Hongmin ZhangDepartment of Elderly Health Management, Shenzhen Center for Chronic Disease Control, Shenzhen, Guangdong, 518020, China.
Ping LiDepartment of Elderly Health Management, Shenzhen Center for Chronic Disease Control, Shenzhen, Guangdong, 518020, China.
Jian XuDepartment of Elderly Health Management, Shenzhen Center for Chronic Disease Control, Shenzhen, Guangdong, 518020, China.ORCID 0000-0001-5727-8191
Zhiguang ZhaoAdministration Office, Shenzhen Center for Chronic Disease Control, Shenzhen, Guangdong, 518020, China.ORCID 0000-0002-9901-0940
Shenzhen Chronic Disease Prevention Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsSarcopenia has been found to be frequently associated with co-morbidity among patients with heart failure (HF). However, there remain insufficient data to accurately estimate the global prevalence of sarcopenia in HF. Therefore, the purpose of this research was to conduct a systematic review and meta-analysis to estimate the current overall prevalence of sarcopenia in patients with HF. METHODS AND

resultsWe searched relevant databases for studies published up to 13 July 2020, assessing sarcopenia in vpatients with HF. After careful screening, data of included articles were extracted with a predesigned Excel form. Then the pooled prevalence of sarcopenia in patients with HF was calculated using the random-effects model. The Q test was used to assess the heterogeneity, and I

conclusionsSarcopenia was a common condition in patients with HF, and the prevalence of hospitalized patients was higher than for ambulatory patients. Early detection of sarcopenia was therefore important in patients with HF, and it was important to implement interventions so that physical therapists or managerial dieticians can easily be introduced into clinical practice.

Indexed as

Heart FailureSarcopeniaComorbidityHumansPrevalenceHeart failureMeta-analysisMultimorbidityMuscle wastingSarcopenia

Identifiers

PMID33576177
PMCPMC8006658
OpenAlexW3127975826

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.