ArticleContact dermatitis2021
Skin exposure to scented products used in daily life and fragrance contact allergy in the European general population - The EDEN Fragrance Study.
Article in Contact dermatitis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 21 citations in OpenAlex.
- Lifestyle Factors in the Clinical Manifestation and Management of Atopic Dermatitis.Archives of internal medicine research · 2025Article
- Fragrance Contact Allergy - A Review Focusing on Patch Testing.Acta dermato-venereologica · 2024Review
- Article
- Indoor Air Sources of Outdoor Air Pollution: Health Consequences, Policy, and Recommendations: An Official American Thoracic Society Workshop Report.Annals of the American Thoracic Society · 2024Article
- A cross-sectional review of contact allergens in popular self-tanning products.International journal of women's dermatology · 2024Article
- GC-MS Determination of Undeclared Phthalate Esters in Commercial Fragrances: Occurrence, Profiles and Assessment of Carcinogenic and Non-Carcinogenic Risk Associated with Their Consumption among Adult Consumers.Molecules (Basel, Switzerland) · 2023Article
- Simultaneous patch testing with fragrance markers in the baseline series and the ingredients of fragrance mixes: An update from southern Sweden.Contact dermatitis · 2022Article
- Predicting the Skin Sensitization Potential of Small Molecules with Machine Learning Models Trained on Biologically Meaningful Descriptors.Pharmaceuticals (Basel, Switzerland) · 2021Article
- Skin exposure to scented products used in daily life and fragrance contact allergy in the European general population - The EDEN Fragrance Study.Contact dermatitis · 2021Article
Corrections and comments
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Authors and funding
9 authors at 6 institutions in 6 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFragrances are widely used in scented products used in daily life with the potential to induce skin sensitization.
objectiveTo evaluate exposure to scented products and to explore associations between exposure and fragrance contact allergy.
methodsA cross-sectional study on individuals from 18 to 74 years of age, who were randomly selected from the general population in five European countries. A random sample (N = 3119) was patch tested and interviewed on exposure to scented products.
resultsFemale participants were strongly associated with exposure to scented products relative to male participants. Participants age 40 years and older showed an inverse association with exposure to scented products. Compared to Sweden, The Netherlands followed by Germany showed the highest overall exposure to scented products. Sensitive skin was associated with exposure to scented products and with fragrance allergy. In univariable regression analysis, exposure to leave-on products and to specific scented product subgroups was significantly associated with fragrance allergy.
conclusionExposure to scented products depends primarily on sex and age. Female sex and sensitive skin are relevant indicators for developing fragrance allergy. Because aggregate exposure, especially to scented leave-on products, may enhance the prevalence of contact allergy to fragrances, further investigations into exposure amounts and frequencies is warranted.
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