ArticleJournal of general internal medicine2021
Severity Scores in COVID-19 Pneumonia: a Multicenter, Retrospective, Cohort Study.
Article in Journal of general internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Impact of vitamin D supplementation on the clinical outcomes of COVID-19 pneumonia patients: a single-center randomized controlled trial.BMC complementary medicine and therapies · 2024Trial
- Development and internal validation of a Viremia-Integrated Risk Assessment (VIRA score) for predicting mortality at diagnosis of COVID-19 pneumonia.Pneumonia (Nathan Qld.) · 2026Article
- Predictive Value of the CURB-65, MuLBSTA, Pneumonia Severity Index Scores and Laboratory Parameters for In-Hospital Mortality in Patients with Diabetes Mellitus and COVID-19 Infection.Journal of clinical medicine · 2026Article
- Association Between Serum Ferritin and Disease Severity in COVID-19 Patients in Bangladesh: A Cross-Sectional Study.Cureus · 2026Article
- Predictability of Severity Scores in Patients over 70 Years Old with COVID-19 Infection: Results from a Single-Center Retrospective Observational Study.Journal of clinical medicine · 2026Article
- Severity Scores in SARS-CoV-2 Infection-A Comprehensive Bibliometric Review and Visualization Analysis.Epidemiologia (Basel, Switzerland) · 2026Review
- Article
- The Impact of MELD, PESI, PSI, and DIC Scores on Predicting Pulmonary Thromboembolism and Mortality Rate in COVID-19 Pneumonia.Tanaffos · 2025Article
- The Predictive Performance of Risk Scores for the Outcome of COVID-19 in a 2-Year Swiss Cohort.Biomedicines · 2024Article
- Time‑dependent ROC curve analysis to determine the predictive capacity of seven clinical scales for mortality in patients with COVID‑19: Study of a hospital cohort with very high mortality.Biomedical reports · 2024Article
- Presepsin as a prognostic biomarker in COVID-19 patients: combining clinical scoring systems and laboratory inflammatory markers for outcome prediction.Virology journal · 2024Article
- Machine learning-based derivation and validation of three immune phenotypes for risk stratification and prognosis in community-acquired pneumonia: a retrospective cohort study.Frontiers in immunology · 2024Article
- CAP-PIRO Scoring System's Performance in Predicting Prognosis and Severity of Community-Acquired Pneumonia: A Single-Center Prospective Study.Infection and drug resistance · 2024Article
- Predictive performance of SOFA (Sequential Organ Failure Assessment) and qSOFA (quick Sequential Organ Failure Assessment) for in-hospital mortality in ICU patients with COVID-19 of referral center in the north of Iran a retrospective study.Annals of medicine and surgery (2012) · 2023Article
- Improving prediction of COVID-19 mortality using machine learning in the Spanish SEMI-COVID-19 registry.Internal and emergency medicine · 2023Article
- Serum Total Antioxidant Capacity (TAC) and TAC/Lymphocyte Ratio as Promising Predictive Markers in COVID-19.International journal of molecular sciences · 2023Article
- Validation of the Barthel Index as a Predictor of In-Hospital Mortality among COVID-19 Patients.Healthcare (Basel, Switzerland) · 2023Article
- Validation of the qSOFA and CRB-65 in SARS-CoV-2-infected community-acquired pneumonia.ERJ open research · 2023Article
- COVID-19 and Vaccination Status in Lysosomal Storage Diseases: A Single-Center Experience.Turkish archives of pediatrics · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
26 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIdentification of patients on admission to hospital with coronavirus infectious disease 2019 (COVID-19) pneumonia who can develop poor outcomes has not yet been comprehensively assessed.
objectiveTo compare severity scores used for community-acquired pneumonia to identify high-risk patients with COVID-19 pneumonia.
designPSI, CURB-65, qSOFA, and MuLBSTA, a new score for viral pneumonia, were calculated on admission to hospital to identify high-risk patients for in-hospital mortality, admission to an intensive care unit (ICU), or use of mechanical ventilation. Area under receiver operating characteristics curve (AUROC), sensitivity, and specificity for each score were determined and AUROC was compared among them.
participantsPatients with COVID-19 pneumonia included in the SEMI-COVID-19 Network. KEY
resultsWe examined 10,238 patients with COVID-19. Mean age of patients was 66.6 years and 57.9% were males. The most common comorbidities were as follows: hypertension (49.2%), diabetes (18.8%), and chronic obstructive pulmonary disease (12.8%). Acute respiratory distress syndrome (34.7%) and acute kidney injury (13.9%) were the most common complications. In-hospital mortality was 20.9%. PSI and CURB-65 showed the highest AUROC (0.835 and 0.825, respectively). qSOFA and MuLBSTA had a lower AUROC (0.728 and 0.715, respectively). qSOFA was the most specific score (specificity 95.7%) albeit its sensitivity was only 26.2%. PSI had the highest sensitivity (84.1%) and a specificity of 72.2%.
conclusionsPSI and CURB-65, specific severity scores for pneumonia, were better than qSOFA and MuLBSTA at predicting mortality in patients with COVID-19 pneumonia. Additionally, qSOFA, the simplest score to perform, was the most specific albeit the least sensitive.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.