Evidence map›Paper›PMID 33575743›Full record

ReviewInteractive cardiovascular and thoracic surgery2021

Narrative review on endovascular techniques for left subclavian artery revascularization during thoracic endovascular aortic repair and risk factors for postoperative stroke.

Mario D'Oria, Kevin Mani, Randall DeMartino, Martin Czerny, Konstantinos P Donas, Anders Wanhainen, Sandro Lepidi

Open access · bronzeAbstract readReview
In one paragraph

Review in Interactive cardiovascular and thoracic surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Pooled it
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  3. The Management of Left Subclavian Artery in Aortic Open and Endovascular Surgery.Journal of cardiovascular development and disease · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 4 countries.

Mario D'OriaDepartment of Surgical Sciences, Section of Vascular Surgery, Uppsala University, Uppsala, Sweden.ORCID 0000-0002-7156-7827
Kevin ManiDepartment of Surgical Sciences, Section of Vascular Surgery, Uppsala University, Uppsala, Sweden.
Randall DeMartinoDivision of Vascular and Endovascular Surgery, Gonda Vascular Center, Mayo Clinic Rochester Campus, Rochester, MN, USA.
Martin CzernyDivision of Cardiovascular Surgery, University Heart Center Freiburg, Bad Krozingen, Freiburg, Germany.
Konstantinos P DonasDepartment of Vascular Surgery, Asklepios Clinic Langen, Goethe-University of Frankfurt, Langen, Germany.
Anders WanhainenDepartment of Surgical Sciences, Section of Vascular Surgery, Uppsala University, Uppsala, Sweden.ORCID 0000-0002-3273-8726
Sandro LepidiDivision of Vascular and Endovascular Surgery, Cardiovascular Department, University of Trieste Medical School, Trieste, Italy.
Uppsala University · SEGoethe University Frankfurt · DEMayo Clinic · USUniversitäts-Herzzentrum Freiburg-Bad Krozingen · DEUniversity of Trieste · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this study was to present a narrative review on endovascular techniques (ET) for revascularization of the left subclavian artery (LSA) during zone 2 thoracic endovascular aortic repair (TEVAR) and on risk factors for postoperative stroke following TEVAR procedures.

methodsNon-systematic search of the literature from the PubMed, Ovid and Scopus databases to identify relevant English-language articles fully published in the period 1 January 2010-1 August 2020.

resultsCurrent general agreement is that LSA revascularization should be always attempted in the elective setting. Under urgent circumstances, it can be delayed but might be considered during the same session on a case-by-case basis. Three ET are currently available: (i) chimney/snorkels (also known as parallel grafts), (ii) fenestrations or branches and (iii) proximal scallops. The main issue with ET is the potential for increased peri-operative stroke risk owing to increased manipulation within the aortic arch. Also, they are relatively novel and further assessment of their long-term durability is needed. Intra-operative embolism and loss of left vertebral artery perfusion are hypothesized as the main causes of stroke in patients undergoing TEVAR.

conclusionsThe overall risk of stroke seems higher without LSA revascularization during zone 2 TEVAR. As LSA revascularization might have a direct effect in preventing posterior stroke, it should be routinely performed in elective cases, while a case-by-case evaluation can be made under urgent circumstances. While ET can provide effective options for LSA revascularization during zone 2 TEVAR, they are novel and need further durability assessment. Stroke after TEVAR is a multifactorial pathological process and preventing TEVAR-related cerebral injury remains a significant unmet clinical need.

Indexed as

Blood Vessel Prosthesis ImplantationEndovascular ProceduresStrokeAorta, ThoracicHumansRetrospective StudiesRisk FactorsSubclavian ArteryTime FactorsTreatment OutcomeLeft subclavian arteryStrokeTEVARThoracic aorta

Identifiers

PMID33575743
PMCPMC8691528
OpenAlexW3127956358

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.