ArticleNAR genomics and bioinformatics2020
A new phylogenetic protocol: dealing with model misspecification and confirmation bias in molecular phylogenetics.
Article in NAR genomics and bioinformatics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Phylogenetic Accuracy Under Non-stationary and Non-homogeneous Conditions: A Simulation Study.Systematic biology · 2026Article
- When the Past Fades: Detecting Phylogenetic Signal with SatuTe.Molecular biology and evolution · 2025Article
- Phylogenetic Signal in Primate Tooth Enamel Proteins and its Relevance for Paleoproteomics.Genome biology and evolution · 2025Article
- A bird's-eye view: exploration of the flavin-containing monooxygenase superfamily in common wheat.Frontiers in plant science · 2024Article
- DEPP: Deep Learning Enables Extending Species Trees using Single Genes.Systematic biology · 2023Article
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Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Molecular phylogenetics plays a key role in comparative genomics and has increasingly significant impacts on science, industry, government, public health and society. In this paper, we posit that the current phylogenetic protocol is missing two critical steps, and that their absence allows model misspecification and confirmation bias to unduly influence phylogenetic estimates. Based on the potential offered by well-established but under-used procedures, such as assessment of phylogenetic assumptions and tests of goodness of fit, we introduce a new phylogenetic protocol that will reduce confirmation bias and increase the accuracy of phylogenetic estimates.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.