Evidence map›Paper›PMID 33575466›Full record

ArticleMolecular therapy oncolytics2021

Association between NER pathway gene polymorphisms and neuroblastoma risk in an eastern Chinese population.

Chunlei Zhou, Yizhen Wang, Lili He, Jinhong Zhu, Jinghang Li, Yingzi Tang, Haixia Zhou, Jing He, Haiyan Wu

Abstract read
In one paragraph

Article in Molecular therapy oncolytics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Genetic variants inCancer innovation · 2022
    Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chunlei ZhouDepartment of Pathology, Children's Hospital of Nanjing Medical University, Nanjing 210008, Jiangsu, China.
Yizhen WangDepartment of Pathology, Anhui Provincial Children's Hospital, Hefei 230051, Anhui, China.
Lili HeDepartment of Pathology, Children's Hospital of Nanjing Medical University, Nanjing 210008, Jiangsu, China.
Jinhong ZhuDepartment of Clinical Laboratory, Biobank, Harbin Medical University Cancer Hospital, Harbin 150040, Heilongjiang, China.
Jinghang LiDepartment of Cardiovascular Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu, China.
Yingzi TangDepartment of Pathology, Children's Hospital of Nanjing Medical University, Nanjing 210008, Jiangsu, China.
Haixia ZhouDepartment of Hematology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou 325027, Zhejiang, China.
Jing HeDepartment of Pediatric Surgery, Guangzhou Institute of Pediatrics, Guangdong Provincial Key Laboratory of Research in Structural Birth Defect Disease, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou 510623, Guangdong, China.
Haiyan WuDepartment of Pathology, Children's Hospital of Nanjing Medical University, Nanjing 210008, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuroblastoma is a common childhood malignancy. Nucleotide excision repair (NER) polymorphisms have been shown to influence cancer susceptibility by modifying DNA repair efficiency. To investigate the association of NER gene polymorphisms with neuroblastoma risk, we constructed a three-center case-control study. A total of 19 candidate single-nucleotide polymorphisms (SNPs) in NER genes were analyzed. Odds ratios (ORs) and 95% confidential intervals (CIs) were calculated to evaluate the associations. We identified five independent SNPs that were significantly associated with neuroblastoma risk, including

Indexed as

neuroblastomanucleotide excision repairpolymorphismsusceptibility

Identifiers

PMID33575466
PMCPMC7851491

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.