Evidence map›Paper›PMID 33575413›Full record

ReviewAIMS public health2021

A rapid review of recent advances in diagnosis, treatment and vaccination for COVID-19.

Srikanth Umakanthan, Vijay Kumar Chattu, Anu V Ranade, Debasmita Das, Abhishekh Basavarajegowda, Maryann Bukelo

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in AIMS public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05502081 (Clinical Study to Evaluate the Possible Efficacy and Safety of Antibodies Combination), which is not on this map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05502081 phase4completednot on this mapstarted 2022, after this paper: background citation

Clinical Study to Evaluate the Possible Efficacy and Safety of Antibodies Combination (Casirivimab and Imdevimab) Versus Standard Antiviral Therapy (Remdesivir and Favipravir) as Antiviral Agent Against Corona Virus 2 Infection in Hospitalized COVID-19 Patients

TypeinterventionalSponsorMansoura University HospitalRan2022 to 2022Enrolled265ConditionsCOVID-19ArmsCasirivimab and Imdevimab Drug Combination, Remdesivir, Favipiravir
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 59 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Current clinical status of new COVID-19 vaccines and immunotherapy.Environmental science and pollution research international · 2022
    Review
  12. Recent advances in point of care testing for COVID-19 detection.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 4 countries.

Srikanth UmakanthanDepartment of Paraclinical Sciences, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago, West Indies.
Vijay Kumar ChattuDepartment of Medicine, Temerty Faculty of Medicine, University of Toronto, Toronto, ON M5G2C4, Canada.
Anu V RanadeDepartment of Basic Medical Sciences, College of Medicine, University of Sharjah, PO Box 27272, USA.
Debasmita DasDepartment of Pathology and Laboratory Medicine, Nuvance Health Danbury Hospital Campus, Connecticut, Zip 06810, USA.
Abhishekh BasavarajegowdaDepartment of Transfusion Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, PIN-605006, India.
Maryann BukeloDepartment of Anatomical Pathology, Eric Williams Medical Sciences Complex, North Central Regional Health Authority, Trinidad and Tobago, West Indies.
Jawaharlal Institute of Post Graduate Medical Education and Research · INDanbury Hospital · USUniversity of the West Indies · TTUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

COVID-19 is caused by SARS-CoV-2, which originated in Wuhan, Hubei province, Central China, in December 2019 and since then has spread rapidly, resulting in a severe pandemic. The infected patient presents with varying non-specific symptoms requiring an accurate and rapid diagnostic tool to detect SARS-CoV-2. This is followed by effective patient isolation and early treatment initiation ranging from supportive therapy to specific drugs such as corticosteroids, antiviral agents, antibiotics, and the recently introduced convalescent plasma. The development of an efficient vaccine has been an on-going challenge by various nations and research companies. A literature search was conducted in early December 2020 in all the major databases such as Medline/PubMed, Web of Science, Scopus and Google Scholar search engines. The findings are discussed in three main thematic areas namely diagnostic approaches, therapeutic options, and potential vaccines in various phases of development. Therefore, an effective and economical vaccine remains the only retort to combat COVID-19 successfully to save millions of lives during this pandemic. However, there is a great scope for further research in discovering cost-effective and safer therapeutics, vaccines and strategies to ensure equitable access to COVID-19 prevention and treatment services.

Indexed as

Antigen testBCGcoronavirusdiagnosisgenomeReverse Transcription Polymerase Chain Reactiontherapyvaccine

Identifiers

PMID33575413
PMCPMC7870385
OpenAlexW3126998389

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.