ArticleBioMed research international2021
Orthokeratology and Low-Intensity Laser Therapy for Slowing the Progression of Myopia in Children.
Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 7 syntheses or guidelines pooled it, 121 citations in OpenAlex.
- Duration-Dependent Efficacy and Clinical Safety of Repeated Low-Level Red-Light Therapy for Paediatric Myopia: A Systematic Review and Meta-Analysis.Clinical & experimental ophthalmology · 2026Pooled it
- Exploring the efficacy of repeated low-level red-light therapy in retarding childhood myopia progression: updated systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- Efficacy comparison of atropine, orthokeratology and repeated low-level red-light therapy for myopia control in children: a systematic review and network meta-analysis.The British journal of ophthalmology · 2025Pooled it
- Repeated low-level red-light therapy vs. conventional treatments for myopic control in children: a systematic review and meta-analysis.Scientific reports · 2025Pooled it
- Effects of repeated low-level red light therapy on myopia progression in children: a systematic review and meta-analysis.Frontiers in medicine · 2025Pooled it
- Light Therapy for Myopia Prevention and Control: A Systematic Review on Effectiveness, Safety, and Implementation.Translational vision science & technology · 2024Pooled it
- Efficacy of Repeated Low-Level Red Light (RLRL) therapy on myopia outcomes in children: a systematic review and meta-analysis.BMC ophthalmology · 2024Pooled it
- Effect of Repeated Low-Level Red Light Versus 0.01% Topical Atropine on Myopia Progression: A Randomized Crossover-Controlled Trial.Translational vision science & technology · 2025Trial
- Short-term effectiveness and safety of photobiomodulation on low-to-moderate myopia.Lasers in medical science · 2025Trial
- Effect of Repeated Low-level Red Light on Myopia Prevention Among Children in China With Premyopia: A Randomized Clinical Trial.JAMA network open · 2023Trial
- Photobiomodulation therapy retarded axial length growth in children with myopia: evidence from a 12-month randomized controlled trial evidence.Scientific reports · 2023Trial
- Effects of Long-Term Wear and Discontinuation of Orthokeratology Lenses on the Eyeball Parameters in Children with Myopia.International journal of medical sciences · 2023Trial
- Sustained and rebound effect of repeated low-level red-light therapy on myopia control: A 2-year post-trial follow-up study.Clinical & experimental ophthalmology · 2022Trial
- Efficacy Comparison of Repeated Low-Level Red Light and Low-Dose Atropine for Myopia Control: A Randomized Controlled Trial.Translational vision science & technology · 2022Trial
- Effect of Photobiomodulation‑Based LED on Myopia Control in Children: An Exploratory Randomized Clinical Trial.Ophthalmology and therapy · 2026Article
- Photobiomodulation therapy for children's eye and vision conditions.Eye (London, England) · 2026Article
- Ocular Transmission of Red and Violet Light: Insights into Light-Based Myopia Therapies.Translational vision science & technology · 2026Article
- Review
- Association between myopia and refractive parameters with eye behaviors in childhood aged 6 ~ 9 years: a follow-up study in Beijing.BMC public health · 2026Article
- Establishing a prediction model for the therapeutic outcomes of short-term and long-term orthokeratology treatment: using baseline data and changes in AL as dynamic variables.BMC medical informatics and decision making · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Orthokeratology (OK) is widely used to slow the progression of myopia. Low-level laser therapy (LLLT) provides sufficient low energy to change the cellular function. This research is aimed at verifying the hypothesis that LLLT treatment could control myopia progression and comparing the abilities of OK lenses and LLLT to control the refractive error of myopia. Eighty-one children (81 eyes) who wore OK lenses, 74 children (74 eyes) who underwent LLLT treatment, and 74 children (74 eyes) who wore single-vision distance spectacles for 6 months were included. Changes in axial length (AL) were 0.23 ± 0.06 mm for children wearing spectacles, 0.06 ± 0.15 mm for children wearing OK lens, and -0.06 ± 0.15 mm for children treated with LLLT for 6 months. Changes in subfoveal choroidal thickness (SFChT) observed at the 6-month examination were -16.84 ± 7.85
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.