Evidence map›Paper›PMID 33575353›Full record

ArticleBioMed research international2021

Development, Biological Characterization, and Immunological Evaluation of Virosome Vaccine against Newcastle Disease in Pakistan.

Muhammad Hidayat Rasool, Asif Mehmood, Muhammad Saqalein, Muhammad Atif Nisar, Ahmad Almatroudi, Mohsin Khurshid

Abstract read
In one paragraph

Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Muhammad Hidayat RasoolDepartment of Microbiology, Government College University Faisalabad, Pakistan.ORCID https://orcid.org/0000-0002-6324-1798
Asif MehmoodDepartment of Microbiology, Government College University Faisalabad, Pakistan.
Muhammad SaqaleinDepartment of Microbiology, Government College University Faisalabad, Pakistan.ORCID https://orcid.org/0000-0001-7247-8511
Muhammad Atif NisarDepartment of Microbiology, Government College University Faisalabad, Pakistan.ORCID https://orcid.org/0000-0002-3870-7314
Ahmad AlmatroudiDepartment of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah, Saudi Arabia.ORCID https://orcid.org/0000-0002-1491-6402
Mohsin KhurshidDepartment of Microbiology, Government College University Faisalabad, Pakistan.ORCID https://orcid.org/0000-0002-3196-2857

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Newcastle disease (ND) is a highly fatal, infectious, viral disease, and despite immunization with live and inactivated vaccines, the disease is still endemic, causing heavy morbidity and mortality leading to huge economic losses to the poultry industry in Pakistan. Therefore, the present study was aimed for the first time in the country at using novel virosomal technology to develop the ND vaccine using an indigenous highly virulent strain of the virus. ND virosome was prepared using Triton X-100, and SM2 Bio-Beads were used to remove the detergent and reconstitute the viral membrane into virosome. Confirmation was done by transmission electron microscopy and protein analysis by SDS-PAGE.

Indexed as

Newcastle DiseasePoultry DiseasesVaccines, VirosomeAnimalsAntibodies, ViralChickensNewcastle disease virusPakistanVirosomesAntibodies, ViralVaccines, VirosomeVirosomes

Identifiers

PMID33575353
PMCPMC7864732

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.