ArticleBioMed research international2021
The Predictive Value of Interleukin-6 and Neutrophil-Lymphocyte Ratio in Patients with Severe and Extremely Severe Oral and Maxillofacial Space Infections.
Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.
- Neutrophil to lymphocyte ratio in odontogenic infection: a systematic review.Head & face medicine · 2024Pooled it
- Orbital and Maxillofacial Soft Tissue Infection Caused by Methicillin-ResistantCase reports in medicine · 2025Article
- Metagenomic analysis reveals severity-dependent microbial succession and correlation with host inflammatory response in oral and maxillofacial space infections.Frontiers in cellular and infection microbiology · 2025Article
- When is surgical intervention needed in oral and maxillofacial space infection patients? A retrospective case control study in 46 patients.BMC oral health · 2024Article
- Negative pressure sealing drainage technology combined with adequate irrigation for oral and maxillofacial space infection can improve serum inflammatory factor levels.American journal of translational research · 2023Article
- Oral and Maxillofacial Infections-A Bacterial and Clinical Cross-Section.Journal of clinical medicine · 2022Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the correlation between clinical manifestation and neutrophil-lymphocyte ratio, C-reactive protein (CRP), and interleukin-6 (IL-6) in the patients with severe and extremely severe oral and maxillofacial space infection (OMSI).
methodsIn this retrospective study, we included 18 patients with severe and extremely severe OMSI from November 2012 to October 2018. Pearson or Spearman correlation coefficients were calculated to measure the association between the number of complications and locations and the number and percentage of lymphocyte, leukocyte, neutrophil, eosinophil, basophil, monocyte, CRP, and IL-6. A multivariable regression model was used to predict the number of complications and locations from these measures.
resultsIL-6 was positively correlated with neutrophil-lymphocyte ratio (
conclusionsThe neutrophil-lymphocyte ratio and IL-6 contributed to the assessment of general condition in severe and profound OMSI patients. These parameters can be used as predictors to evaluate the severity of OMSI.
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