Evidence map›Paper›PMID 33575076›Full record

ArticleAmerican journal of cancer research2021

Adamantane-linked isothiourea derivatives suppress the growth of experimental hepatocellular carcinoma

Hanan M Hassan, Lamya H Al-Wahaibi, George Sg Shehatou, Ali A El-Emam

Open access · greenAbstract read
In one paragraph

Article in American journal of cancer research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 15 citations in OpenAlex.

  1. Asialoglycoprotein receptor-mediated delivery of copper to hepatic tumors exerted inhibitory effect on tumor growth and progression.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Hanan M HassanDepartment of Pharmacology and Biochemistry, Faculty of Pharmacy, Delta University for Science and Technology International Costal Road, Gamasa 11152, Mansoura, Egypt.
Lamya H Al-WahaibiDepartment of Chemistry, College of Sciences, Princess Nourah bint Abdulrahman University Riyadh 11671, Saudi Arabia.
George Sg ShehatouDepartment of Pharmacology and Biochemistry, Faculty of Pharmacy, Delta University for Science and Technology International Costal Road, Gamasa 11152, Mansoura, Egypt.
Ali A El-EmamDepartment of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University Mansoura 35516, Egypt.
Mansoura University · EGPrincess Nourah bint Abdulrahman University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study,

Indexed as

Adamantyl isothioureaepoxide hydrolasehepatocellular carcinomaMyD88NF-κBTLR4

Identifiers

PMID33575076
PMCPMC7868765
OpenAlexW3128360672

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.