ArticleStroke research and treatment2021
Predictive Value of the Alberta Stroke Program Early CT Score (ASPECTS) in the Outcome of the Acute Ischemic Stroke and Its Correlation with Stroke Subtypes, NIHSS, and Cognitive Impairment.
Article in Stroke research and treatment, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04235920 (Correlation of Alberta Stroke Program Early CT Score), which is not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Correlation of Alberta Stroke Program Early CT Score (ASPECTS) With Cognitive Impairment and Outcome of Acute Ischemic Stroke
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Outcomes of Patients With Atrial Fibrillation Following Thrombectomy for Stroke: A Systematic Review and Meta-analysis.JAMA network open · 2023Pooled it
- Functional Outcome Prediction in Acute Ischemic Stroke Using a Fused Imaging and Clinical Deep Learning Model.Stroke · 2023Trial
- Copeptin in acute ischemic stroke: a surrogate marker of AVP-system activation with temporal dynamics and clinical implications.Journal of thrombosis and thrombolysis · 2026Review
- Refined AI-ASPECTS with modified atlas and lesion-load thresholds: advancing acute ischemic stroke imaging and prognostic prediction.BMC medicine · 2026Article
- Influence of deep learning image reconstruction and adaptive statistical iterative reconstruction-V on automated Alberta stroke program early CT score- evaluation.Neuroradiology · 2026Article
- Analysis of cognitive function trajectories and influencing factors in elderly patients with ischemic stroke: a prospective longitudinal study.Frontiers in aging neuroscience · 2026Article
- NIHSS mismatch as a predictor of early neurological improvement after mechanical thrombectomy.Scientific reports · 2025Article
- Comprehensive Venous Outflow Evaluation Predicts Stroke Outcome After Optimal Endovascular Ischemic Stroke Treatment.Translational stroke research · 2025Article
- Dual-Energy CT-Based Thrombus Radiomics Can Predict Functional Outcome of Intravenous Thrombolysis in Acute Ischemic Stroke.Translational stroke research · 2025Article
- Article
- Imaging-based machine learning to evaluate the severity of ischemic stroke in the middle cerebral artery territory.BMC medical imaging · 2025Article
- Automatic prediction of stroke treatment outcomes: latest advances and perspectives.Biomedical engineering letters · 2025Review
- Analyzing the serum biochemical factors that influence early neurological deterioration in ischemic Stroke patients and developing a nomogram prediction model.Journal of medical biochemistry · 2025Article
- Effect of early neuroendovascular team involvement in acute stroke protocol: a retrospective study.Frontiers in neurology · 2025Article
- Utility of the ASPECT Score for Predicting Intracranial Hemorrhage Following Intravenous Thrombolysis in Patients with Suspected MCA Infarction: Insights from the Northern Thai Stroke Registry.Journal of multidisciplinary healthcare · 2024Article
- Is aspiration an effective acute stroke treatment in older adults?Frontiers in neurology · 2023Article
- Association of Lesion Topography with Functional Outcomes in Acute Ischemic Stroke Patients Considered for, or Receiving, Reperfusion Therapy: A Meta-Analysis.Neurology international · 2022Article
- Predictors of 30-day mortality among patients with stroke admitted at a tertiary teaching hospital in Northwestern Tanzania: A prospective cohort study.Frontiers in neurology · 2022Article
- Performance of serial CT ASPECTS for predicting stroke outcomes in patients with thrombolyzed acute ischemic stroke.Journal of neurosciences in rural practiceArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis study is aimed at correlating ASPECTS with mortality and morbidity in patients with acute middle cerebral artery territory infarction and at determining the cutoff value of ASPECTS that may predict the outcome.
methods150 patients diagnosed with acute middle cerebral artery territory infarction were involved in this study. Risk factors, initial NIHSS, and GCS were determined. An initial or follow-up noncontrast CT brain was done and assessed by ASPECTS. Outcomes were determined by mRS during the follow-up of cases after 3 months. Correlations of ASPECTS and outcome variables were done by Spearman correlation. Logistic regression analysis and ROC curve were done to detect the cutoff value of ASPECTS that predicts unfavorable outcomes.
resultsThe most common subtypes of ischemic strokes were lacunar stroke in 66 patients (44%), cardioembolic stroke in 39 patients (26%), and LAA stroke in 30 cases (20%). The cardioembolic stroke had a statistically significant lower ASPECT score than other types of ischemic strokes (
conclusionsASPECTS is a valuable and appropriate technique for the evaluation of the prognosis in acute ischemic stroke. Patients with high ASPECTS values are more likely to attain favorable outcomes, and the cutoff value of ASPECTS is a strong predictor for unfavorable outcomes. This trial is registered with ClinicalTrials.gov NCT04235920.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.