Evidence map›Paper›PMID 33574819›Full record

ReviewFrontiers in immunology

COVID-19 in Association With Development, Course, and Treatment of Systemic Autoimmune Rheumatic Diseases.

Katja Lakota, Katja Perdan-Pirkmajer, Alojzija Hočevar, Snezna Sodin-Semrl, Žiga Rotar, Saša Čučnik, Polona Žigon

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 25 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Polymyalgia Rheumatica Post-SARS-CoV-2 Infection.Case reports in immunology · 2024
    Article
  5. The Impact of the COVID-19 Pandemic on Inflammatory Rheumatic Diseases.Journal of clinical practice and research · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Immunological map in COVID-19.Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi · 2021
    Review
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Katja LakotaDepartment of Rheumatology, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Katja Perdan-PirkmajerDepartment of Rheumatology, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Alojzija HočevarDepartment of Rheumatology, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Snezna Sodin-SemrlDepartment of Rheumatology, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Žiga RotarDepartment of Rheumatology, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Saša ČučnikDepartment of Rheumatology, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Polona ŽigonDepartment of Rheumatology, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Ljubljana University Medical Centre · SIUniversity of Ljubljana · SIUniversity of Primorska · SI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autoimmune diseases and infections are often closely intertwined. Patients with autoimmune diseases are more susceptible to infections due to either active autoimmune disease or the medications used to treat them. Based on infections as environmental triggers of autoimmunity, an autoimmune response would also be expected in COVID-19. Although some studies have shown the occurance of autoantibodies and the possible development of autoimmune diseases after SARS-CoV-2 infection, current data suggest that the levels of autoantibodies following SARS-CoV-2 infection is comparable to that of some other known infections and that the autoantibodies might only be transient. The risk of SARS-CoV-2 infection in patients with a systemic autoimmune rheumatic disease (SARD) appears slightly higher compared to the general population and the course of COVID-19 disease does not seem to be very different, however, specific therapies such as glucocorticoids and anti-TNF might modulate the risk of hospitalization/death. Cytokine release syndrome is a severe complication in COVID-19. Many drugs used for the treatment of SARD are directly or indirectly targeting cytokines involved in the cytokine release syndrome, therefore it has been suggested that they could also be effective in COVID-19, but more evidence on the use of these medications for the treatment of COVID-19 is currently being collected.

Indexed as

Autoimmune DiseasesCOVID-19COVID-19 Drug TreatmentRheumatic DiseasesHumansSARS-CoV-2antiphospholipid antibodiesautoantibodiesCOVID-19disease-modifying antirheumatic drugsincidencepediatric multisystem inflammatory syndrome in childrensystemic autoimmune rheumatic diseasestherapy

Identifiers

PMID33574819
PMCPMC7870870
OpenAlexW3121359554

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.