Evidence map›Paper›PMID 33574739›Full record

ArticleFrontiers in neuroscience2020

Electro-Acupuncture Attenuates Chronic Stress Responses

Yu Yang, Haijie Yu, Reji Babygirija, Bei Shi, Weinan Sun, Xiaojiao Zheng, Jun Zheng

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
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  4. Article
  5. Review
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Yu YangDepartment of Physiology, School of Life Sciences, China Medical University, Shenyang, China.
Haijie YuDepartment of Cardiology, First Affiliated Hospital, China Medical University, Shenyang, China.
Reji BabygirijaDepartment of Surgery, Medical College of Wisconsin and Zablocki VA Medical Center, Milwaukee, WI, United States.
Bei ShiDepartment of Physiology, School of Life Sciences, China Medical University, Shenyang, China.
Weinan SunDepartment of Physiology, School of Life Sciences, China Medical University, Shenyang, China.
Xiaojiao ZhengDepartment of Physiology, School of Life Sciences, China Medical University, Shenyang, China.
Jun ZhengDepartment of Physiology, School of Life Sciences, China Medical University, Shenyang, China.
China Medical University · CNMilwaukee VA Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stress can increase the release of corticotropin-releasing factor (CRF) in the hypothalamus, resulting in attenuation of gastric motor functions. In contrast, central neuropeptide Y (NPY) can reduce the biological actions of CRF, and in turn weaken stress responses. Although electroacupuncture (EA) at stomach 36 (ST-36) has been shown to have anti-stress effects, its mechanism has not yet been investigated. The effect of EA at ST-36 on the hypothalamus-pituitary-adrenal (HPA) axis and gastrointestinal motility in chronic complicated stress (CCS) conditions have not been studied and the inhibitory mechanism of NPY on CRF through the gamma-aminobutyric acid (GABA)

Indexed as

electroacupuncturefunctional dyspepsiagamma-aminobutyric acid A receptorneuropeptide Ystress

Identifiers

PMID33574739
PMCPMC7870494
OpenAlexW3122175996

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.