Evidence map›Paper›PMID 33574697›Full record

ArticleJournal of pain research2021

Safety and Efficacy of Ultrasound-Guided Retrolaminar Block of Multiple Injections in Retroperitoneal Laparoscopic Nephrectomy: A Prospective Randomized Controlled Study.

Dexing Liu, Xinpeng Xu, Yuhang Zhu, Xingxing Liu, Faliang Zhao, Guobiao Liang, Zhaoqiong Zhu

2 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in Journal of pain research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06787898 nacompletednot on this mapstarted 2025, after this paper: background citation

USG-Guided Retrolaminar Block Improves Postoperative Gastrointestinal System Functions in Percutaneous Nephrolithotomy Patients: A Prospective, Randomised, Clinical Study

TypeinterventionalSponsorElazıg Fethi Sekin Sehir HastanesiRan2025 to 2025Enrolled60ConditionsRetrolaminar Block, Percutaneous Nephrolithotomy (PCNL)ArmsGroup R: retrolaminar block performed group, Group C - Placebo
NCT06869889 naactive not recruitingnot on this mapstarted 2025, after this paper: background citation

Fluoroscopy-Guided Retrolaminar Block Versus Local Wound Infiltration for Post Lumbar Discectomy Analgesia: A Double-Blinded, Randomized Trial

TypeinterventionalSponsorZagazig UniversityRan2025 to 2026Enrolled130ConditionsAnalgesia, Disk Herniated Lumbar, Local InfiltrationArmsRetrolaminar plane block, Local wound infiltration
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Dexing LiuSoochow University Medical College, Suzhou, 215000, People's Republic of China.
Xinpeng XuDepartment of Anesthesiology, Affiliated Hospital of Zunyi Medical University, ZunYi, 563000, People's Republic of China.
Yuhang ZhuDepartment of Anesthesiology, Affiliated Hospital of Zunyi Medical University, ZunYi, 563000, People's Republic of China.
Xingxing LiuSoochow University Medical College, Suzhou, 215000, People's Republic of China.ORCID 0000-0002-6035-8253
Faliang ZhaoSoochow University Medical College, Suzhou, 215000, People's Republic of China.
Guobiao LiangSoochow University Medical College, Suzhou, 215000, People's Republic of China.
Zhaoqiong ZhuSoochow University Medical College, Suzhou, 215000, People's Republic of China.ORCID 0000-0002-5654-3739
Zunyi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeUltrasound-guided retrolaminar block (RLB) has the potential to provide postoperative analgesia in retroperitoneal laparoscopic surgery. This study was conducted to evaluate the effects of RLB when compared with local infiltration analgesia (LIA) in retroperitoneal laparoscopic nephrectomy. PATIENTS AND

methodsOne hundred and fifteen patients scheduled for laparoscopic nephrectomy were divided into two groups: the RLB group (n = 57) received an ultrasound-guided RLB, while the LIA group (n = 58) received LIA. At 2, 4, 6, 24, and 48 hours after operation, the maximal visual analog score (VAS), sufentanil and rescue analgesia consumption, and the utilization of patient-controlled intravenous analgesia (PCIA) were assessed. The incidence rates of postoperative nausea and vomiting (PONV); time of leaving bed (at the first instance); and the levels of plasma β-Endorphin (β-EP), Interleukin-1β (IL-1β), and prostaglandin E2 (PEG2) 30 min after extubation were noted.

resultsPatients in the RLB group had significantly lower VAS scores; lower sufentanil cumulative consumption; lower manual addition frequency of PCIA; lower proportion of using rescue analgesia within 48 hours after operation; lower incidence rate of PONV; shorter resuscitation times; earlier time of leaving the bed; and lower β-EP, IL-1 β, and PEG2 levels.

conclusionUltrasound-guided RLB of multiple injections is both safe and controllable for postoperative analgesia after retroperitoneal laparoscopic nephrectomy. When compared with LIA, RLB has better and longer-lasting analgesic effect, lower incidence rates of PONV, and the potential to reduce the level of postoperative inflammatory factors.

trial registrationChina Clinical Trials Registration Center (http://www.chictr.org.cn, No. ChiCTR1800017526, Date of registration: 2018-08-02).

Indexed as

local infiltration anesthesiaretrolaminar blockretroperitoneal laparoscopic nephrectomyultrasound guidance

Identifiers

PMID33574697
PMCPMC7872929
OpenAlexW3127059402

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.