Evidence map›Paper›PMID 33574671›Full record

ArticleNeuropsychiatric disease and treatment2021

Association Between the

Xing Huang, Jie Liu, Jinzhi Cong, Xinhua Zhang

Open access · goldAbstract read
In one paragraph

Article in Neuropsychiatric disease and treatment, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Xing HuangDepartment of Psychology and Psychiatry, Medical College, Qingdao University, Qingdao, People's Republic of China.
Jie LiuDepartment of Psychiatry, Qingdao Mental Health Center, Qingdao, People's Republic of China.
Jinzhi CongHealth Convergence Media Communication Division, Shandong Health Publicity and Education Center, Jinan, People's Republic of China.
Xinhua ZhangDepartment of Psychology and Psychiatry, Medical College, Qingdao University, Qingdao, People's Republic of China.ORCID 0000-0002-3260-500X
Qingdao University · CNQingdao Mental Health Center · CNShandong Mental Health Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObsessive-compulsive disorder (OCD) is a common, serious and genetically related mental illness; the etiology of OCD has not yet reached a definitive conclusion. Multiple evidence suggests that the glutamatergic system plays a major role in the pathophysiology of OCD. However, subsequent studies on the glutamate transporter gene are not consistent. OCD is a heterogeneous disease. To resolve the complex genetic basis of OCD, division the disorder into different subphenotypes is an effective method for studying the pathogenesis of OCD.

methodsWe recruited 438 OCD patients and 465 age- and sex-matched controls from a Chinese Han population.

resultsThe genotype of

conclusionThis study provides suggestive evidence that SLC1A1 may be involved in the development of OCD in the Han population. However, these findings require further replication.

Indexed as

glutamate transporter genehaplotypeobsessive-compulsive disorder

Identifiers

PMID33574671
PMCPMC7872936
OpenAlexW3127278529

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.