Evidence map›Paper›PMID 33574665›Full record

ArticleInternational journal of nanomedicine2021

A Selenium Nanocomposite Protects the Mouse Brain from Oxidative Injury Following Intracerebral Hemorrhage.

Yong Yang, Guoying Deng, Peng Wang, Guangzhao Lv, Rui Mao, Yuhao Sun, Baofeng Wang, Xijian Liu, Liuguan Bian, Dong Zhou

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Nanobiotechnologies for stroke treatment.Nanomedicine (London, England) · 2025
    Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Advances of nanotechnology for intracerebral hemorrhage therapy.Frontiers in bioengineering and biotechnology · 2023
    Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Yong Yang *Department of Neurosurgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, People's Republic of China.ORCID 0000-0002-9093-0396
Guoying Deng *Trauma Center, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, 201620, People's Republic of China.ORCID 0000-0002-1693-8453
Peng WangDepartment of Neurosurgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, People's Republic of China.
Guangzhao LvDepartment of Neurosurgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, People's Republic of China.
Rui MaoDepartment of Neurosurgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, People's Republic of China.
Yuhao SunDepartment of Neurosurgery, Ruijin Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, 200025, People's Republic of China.
Baofeng WangDepartment of Neurosurgery, Ruijin Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, 200025, People's Republic of China.
Xijian LiuCollege of Chemistry and Chemical Engineering, Shanghai University of Engineering Science, Shanghai, 201620, People's Republic of China.ORCID 0000-0001-5856-9142
Liuguan BianDepartment of Neurosurgery, Ruijin Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, 200025, People's Republic of China.
Dong ZhouDepartment of Neurosurgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, People's Republic of China.ORCID 0000-0002-3289-2168
Guangdong Academy of Medical Sciences · CNShanghai Jiao Tong University · CNShanghai University of Engineering Science · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntracerebral hemorrhage (ICH) is a common neurological crisis leading to high mortality and morbidity. Oxidative stress-induced secondary injury plays a critical role in neurological deterioration. Previously, we synthesized a porous Se@SiO

methodsA porous Se@SiO

resultsThe results demonstrated that Se@SiO

conclusionThese results suggested that the porous Se@SiO

Indexed as

AnimalsAntioxidantsApoptosisBiomarkersBlood-Brain BarrierBrainBrain EdemaCell Line, TumorCerebral HemorrhageCytoprotectionDisease Models, AnimalHeminHumansMaleMalondialdehydeMiceAntioxidantsBiomarkersHeminMalondialdehydeNeuroprotective AgentsReactive Oxygen SpeciesSeleniumSilicon Dioxideapoptosisblood–brain barrierbrain edemaoxidative stressselenium nanocomposites

Identifiers

PMID33574665
PMCPMC7871993
OpenAlexW3128544206

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.