Evidence map›Paper›PMID 33574504›Full record

ArticleScientific reports2021

Load-sharing biomechanics of lumbar fixation and fusion with pedicle subtraction osteotomy.

Luigi La Barbera, Hans-Joachim Wilke, Maria Luisa Ruspi, Marco Palanca, Christian Liebsch, Andrea Luca, Marco Brayda-Bruno, Fabio Galbusera, Luca Cristofolini

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Impact of caudal segment bone fusion on rod load at the cranial segment in a two-level spinal interbody fusion construct- a biomechanical study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
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  14. Biomechanical comparison of multi-rod constructs by satellite rod configurations (in-line vs. lateral) and screw types (monoaxial vs. polyaxial) spanning a lumbar pedicle subtraction osteotomy (PSO): is there an optimal configuration?European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Luigi La BarberaLaboratory of Biological Structure Mechanics, Department of Chemistry, Materials and Chemical Engineering "G. Natta", Politecnico Di Milano, Piazza Leonardo da Vinci 32, 20133, Milan, Italy. luigi.labarbera@polimi.it.
Hans-Joachim WilkeInstitute of Orthopaedic Research and Biomechanics, Trauma Research Center Ulm, Ulm University, Ulm, Germany.
Maria Luisa RuspiDepartment of Industrial Engineering, School of Engineering and Architecture, Alma Mater Studiorum, Università Di Bologna, Bologna, Italy.
Marco PalancaDepartment of Industrial Engineering, School of Engineering and Architecture, Alma Mater Studiorum, Università Di Bologna, Bologna, Italy.
Christian LiebschInstitute of Orthopaedic Research and Biomechanics, Trauma Research Center Ulm, Ulm University, Ulm, Germany.
Andrea LucaDepartment of Spine Surgery III, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
Marco Brayda-BrunoDepartment of Spine Surgery III, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
Fabio GalbuseraIRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
Luca CristofoliniDepartment of Industrial Engineering, School of Engineering and Architecture, Alma Mater Studiorum, Università Di Bologna, Bologna, Italy.
Istituto Ortopedico Galeazzi · ITUniversity of Bologna · ITUniversität Ulm · DEPolitecnico di Milano · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pedicle subtraction osteotomy (PSO) is an invasive surgical technique allowing the restoration of a well-balanced sagittal profile, however, the risks of pseudarthrosis and instrumentation breakage are still high. Literature studied primary stability and posterior instrumentation loads, neglecting the load shared by the anterior column, which is fundamental to promote fusion early after surgery. The study aimed at quantifying the load-sharing occurring after PSO procedure across the ventral spinal structures and the posterior instrumentation, as affected by simple bilateral fixation alone, with interbody cages adjacent to PSO level and supplementary accessory rods. Lumbar spine segments were loaded in vitro under flexion-extension, lateral bending, and torsion using an established spine tester. Digital image correlation (DIC) and strain-gauge (SG) analyses measured, respectively, the full-field strain distribution on the ventral surface of the spine and the local strain on posterior primary rods. Ventral strains considerably decreased following PSO and instrumentation, confirming the effectiveness of posterior load-sharing. Supplemental accessory rods considerably reduced the posterior rod strains only with interbody cages, but the ventral strains were unaffected: this indicates that the load transfer across the osteotomy could be promoted, thus explaining the higher fusion rate with decreased rod fracture risk reported in clinical literature.

Indexed as

Biomechanical PhenomenaBiophysicsFemaleHumansLordosisLumbar VertebraeLumbosacral RegionMaleMiddle AgedOsteotomyPedicle ScrewsRange of Motion, ArticularSpinal Fusion

Identifiers

PMID33574504
PMCPMC7878841
OpenAlexW3127639621

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.