ArticleScientific reports2021
Protective effect of snail secretion filtrate against ethanol-induced gastric ulcer in mice.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed, 71 citations in OpenAlex.
- Gastroprotective Effects of Nettle- and Carob-Enriched Snail Mucus in a Rat Model of Gastric Injury: Role of Antioxidant and Anti-Inflammatory Mechanisms.Food science & nutrition · 2026Article
- Anthraquinone Derivative Rufigallol Protects Against Ethanol-Induced Gastric Damage via Modulation of PGEAntioxidants (Basel, Switzerland) · 2026Article
- Protective effect of snail secretion filtrate in an in vitro model of mastitis.Veterinary record open · 2026Article
- Exploring the Multifunctional Benefits of Astaxanthin in Aging, Oxidative Stress, Immune Dysfunction, Gut and Skin Health.Antioxidants (Basel, Switzerland) · 2026Review
- T Helper and Cytotoxic T Cells Play an Important Role in Acute Gastric Injury.Diseases (Basel, Switzerland) · 2025Article
- Chemical Variability and Biological Potential ofMolecules (Basel, Switzerland) · 2025Review
- Toxic effects of Helix aspersa snail egg hydrolyzates obtained by static in vitro digestion on Caco-2 colorectal adenocarcinoma cells.Scientific reports · 2025Article
- Unveiling the therapeutic journey of snail mucus in diabetic wound care.Naunyn-Schmiedeberg's archives of pharmacology · 2025Review
- Green Synthesis of Antimicrobial Silver Nanoparticles (AgNPs) from the Mucus of the Garden SnailMolecules (Basel, Switzerland) · 2025Article
- Chemical Composition and Antiulcer Effects of Filipendula palmata in Mice.Plant foods for human nutrition (Dordrecht, Netherlands) · 2025Article
- Evaluation of anti-ulcer activity of hydromethanol crude extract and solvent fractions of Vicia faba (Fabaceae) seeds in mice.PloS one · 2025Article
- Influence of the extraction method on functional properties of commercial snail secretion filtrates.Scientific reports · 2024Article
- Biological Properties of the Mucus and Eggs ofInternational journal of molecular sciences · 2024Article
- Article
- Alginate Oligosaccharides Protect Gastric Epithelial Cells against Oxidative Stress Damage through Induction of the Nrf2 Pathway.Antioxidants (Basel, Switzerland) · 2024Article
- Article
- One-health approach on the future application of snails: a focus on snail-transmitted parasitic diseases.Parasitology research · 2023Review
- Gastropod Mucus: Interdisciplinary Perspectives on Biological Activities, Applications, and Strategic Priorities.ACS biomaterials science & engineering · 2023Review
- Modulation of the Proliferative Pathway, Neuroinflammation and Pain in Endometriosis.International journal of molecular sciences · 2023Article
- Effect of Pesticide Vinclozolin Toxicity Exposure on Cardiac Oxidative Stress and Myocardial Damage.Toxics · 2023Article
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gastric ulcer or peptic ulcer is a common disease worldwide. Basically, it develops when there is an imbalance between the protective and aggressive factors, especially at the luminal surface of epithelial cells. Thus, there is a constant interest in research new drugs for treatment of gastric ulcer. The snail secretion is a dense mucous, that covers the external surface of the snails, with important functions for the survival of snails. The biological proprieties of snail Helix Aspersa Muller mucus it has been known for centuries to treat human disorders in particular for skin disease. Recently the use of snail mucus has seen a worldwide increase, as a component in cosmetic product and it has been used in particular for the management of wound and skin disorders. In this study we use a murine model of ethanol intragastric administration which has been widely used to test the drugs efficacies and to explore the underlying mechanism for gastric ulcer development. The intragastric ethanol administration causes several mucosal damages and an induction of a severe inflammatory response. Our results show a significant protective effect of snail secretion filtrate in reducing macroscopic and histological lesions, as well the protective effect on mucus content, oxidative stress and inflammatory response. In conclusion this study demonstrate the protective effect of intragastrical snail secretion filtrate, in a model of ethanol-induced gastric ulcer in mice, suggesting its possible useful use in the treatment or prevention of gastric ulcer.
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