Evidence map›Paper›PMID 33574461›Full record

ArticleScientific reports2021

Supercritical carbon dioxide decellularization of plant material to generate 3D biocompatible scaffolds.

Ashlee F Harris, Jerome Lacombe, Sumedha Liyanage, Margaret Y Han, Emily Wallace, Sophia Karsunky, Noureddine Abidi, Frederic Zenhausern

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Decellularized Persian walnut leaf (Frontiers in bioengineering and biotechnology · 2025
    Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Review
  16. Plant Cellulose as a Substrate for 3D Neural Stem Cell Culture.Bioengineering (Basel, Switzerland) · 2023
    Article
  17. Article
  18. Review
  19. Article
  20. Multiple Cell Cultures for MRI Analysis.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ashlee F Harris *Center for Applied NanoBioscience and Medicine, College of Medicine Phoenix, University of Arizona, 475 North 5th Street, Phoenix, AZ, 85004, USA. ashleeharris@arizona.edu.
Jerome Lacombe *Center for Applied NanoBioscience and Medicine, College of Medicine Phoenix, University of Arizona, 475 North 5th Street, Phoenix, AZ, 85004, USA. jlacombe@arizona.edu.
Sumedha LiyanageFiber and Biopolymer Research Institute, Department of Plant and Soil Science, Texas Tech University, Lubbock, TX, USA.
Margaret Y HanCenter for Applied NanoBioscience and Medicine, College of Medicine Phoenix, University of Arizona, 475 North 5th Street, Phoenix, AZ, 85004, USA.
Emily WallaceCenter for Applied NanoBioscience and Medicine, College of Medicine Phoenix, University of Arizona, 475 North 5th Street, Phoenix, AZ, 85004, USA.
Sophia KarsunkySchool of Pharmaceutical Sciences, University of Geneva, Geneva, Switzerland.
Noureddine AbidiFiber and Biopolymer Research Institute, Department of Plant and Soil Science, Texas Tech University, Lubbock, TX, USA.
Frederic ZenhausernCenter for Applied NanoBioscience and Medicine, College of Medicine Phoenix, University of Arizona, 475 North 5th Street, Phoenix, AZ, 85004, USA. ashleeharris@arizona.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of plant-based biomaterials for tissue engineering has recently generated interest as plant decellularization produces biocompatible scaffolds which can be repopulated with human cells. The predominant approach for vegetal decellularization remains serial chemical processing. However, this technique is time-consuming and requires harsh compounds which damage the resulting scaffolds. The current study presents an alternative solution using supercritical carbon dioxide (scCO

Indexed as

Biocompatible MaterialsCarbon DioxideExtracellular MatrixHumansPlant CellsTissue EngineeringTissue ScaffoldsBiocompatible MaterialsCarbon Dioxide

Identifiers

PMID33574461
PMCPMC7878742

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.