ArticleScientific reports2021
Bile acids and oxo-metabolites as markers of human faecal input in the ancient Pompeii ruins.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 10 citations in OpenAlex.
- Article
- Uncovering the Holocene roots of contemporary disease-scapes: bringing archaeology into One Health.Proceedings. Biological sciences · 2023Review
- Metabolic Bile Acid Profile Impairments in Dogs Affected by Chronic Inflammatory Enteropathy.Metabolites · 2023Article
- Analysis of fecal bile acids and metabolites by high resolution mass spectrometry in farm animals and correlation with microbiota.Scientific reports · 2022Article
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Authors and funding
8 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Small organic molecules, lipids, proteins, and DNA fragments can remain stable over centuries. Powerful and sensitive chemical analysis can therefore be used to characterize ancient remains for classical archaeological studies. This bio-ecological dimension of archaeology can contribute knowledge about several aspects of ancient life, including social organization, daily habits, nutrition, and food storage. Faecal remains (i.e. coprolites) are particularly interesting in this regard, with scientists seeking to identify new faecal markers. Here, we report the analysis of faecal samples from modern-day humans and faecal samples from a discharge pit on the site of the ruins of ancient Pompeii. We propose that bile acids and their gut microbiota oxo-metabolites are the most specific steroid markers for detecting faecal inputs. This is due to their extreme chemical stability and their exclusive occurrence in vertebrate faeces, compared to other ubiquitous sterols and steroids.
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