Evidence map›Paper›PMID 33574268›Full record

ArticleNature communications2021

A membrane-bound ankyrin repeat protein confers race-specific leaf rust disease resistance in wheat.

Markus C Kolodziej, Jyoti Singla, Javier Sánchez-Martín, Helen Zbinden, Hana Šimková, Miroslava Karafiátová, Jaroslav Doležel, Julien Gronnier, Manuel Poretti, Gaétan Glauser and 6 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
24.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 137 citations in OpenAlex.

  1. Article
  2. Mechanisms and balanced regulation of plant immunity.Nature reviews. Molecular cell biology · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Progress and innovations of gene cloning in wheat and its close relatives.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 5 countries.

Markus C KolodziejUniversity of Zurich, Department of Plant and Microbial Biology, Zollikerstrasse 107, 8008, Zurich, Switzerland.ORCID http://orcid.org/0000-0003-3155-2935
Jyoti SinglaUniversity of Zurich, Department of Plant and Microbial Biology, Zollikerstrasse 107, 8008, Zurich, Switzerland.
Javier Sánchez-MartínUniversity of Zurich, Department of Plant and Microbial Biology, Zollikerstrasse 107, 8008, Zurich, Switzerland.ORCID http://orcid.org/0000-0002-0284-7219
Helen ZbindenUniversity of Zurich, Department of Plant and Microbial Biology, Zollikerstrasse 107, 8008, Zurich, Switzerland.
Hana ŠimkováInstitute of Experimental Botany of the Czech Academy of Sciences, Centre of the Region Hana for Biotechnological and Agricultural Research, Šlechtitelů 31, 779 00, Olomouc, Czech Republic.ORCID http://orcid.org/0000-0003-4159-7619
Miroslava KarafiátováInstitute of Experimental Botany of the Czech Academy of Sciences, Centre of the Region Hana for Biotechnological and Agricultural Research, Šlechtitelů 31, 779 00, Olomouc, Czech Republic.ORCID http://orcid.org/0000-0003-1177-6472
Jaroslav DoleželInstitute of Experimental Botany of the Czech Academy of Sciences, Centre of the Region Hana for Biotechnological and Agricultural Research, Šlechtitelů 31, 779 00, Olomouc, Czech Republic.ORCID http://orcid.org/0000-0002-6263-0492
Julien GronnierUniversity of Zurich, Department of Plant and Microbial Biology, Zollikerstrasse 107, 8008, Zurich, Switzerland.ORCID http://orcid.org/0000-0002-1429-0542
Manuel PorettiUniversity of Zurich, Department of Plant and Microbial Biology, Zollikerstrasse 107, 8008, Zurich, Switzerland.ORCID http://orcid.org/0000-0001-6915-2238
Gaétan GlauserNeuchâtel Platform of Analytical Chemistry, Université de Neuchâtel, Avenue de Bellevaux 51, 2000, Neuchâtel, Switzerland.
Wangsheng ZhuDepartment of Molecular Biology, Max Planck Institute for Developmental Biology, 72076, Tübingen, Germany.ORCID http://orcid.org/0000-0001-7773-3438
Philipp KösterUniversity of Zurich, Department of Plant and Microbial Biology, Zollikerstrasse 107, 8008, Zurich, Switzerland.ORCID http://orcid.org/0000-0002-1359-822X
Cyril ZipfelUniversity of Zurich, Department of Plant and Microbial Biology, Zollikerstrasse 107, 8008, Zurich, Switzerland.ORCID http://orcid.org/0000-0003-4935-8583
Thomas WickerUniversity of Zurich, Department of Plant and Microbial Biology, Zollikerstrasse 107, 8008, Zurich, Switzerland. wicker@botinst.uzh.ch.ORCID http://orcid.org/0000-0002-6777-7135
Simon G KrattingerKing Abdullah University of Science and Technology (KAUST), Biological and Environmental Science and Engineering Division (BESE), Thuwal, 23955-6900, Kingdom of Saudi Arabia. simon.krattinger@kaust.edu.sa.ORCID http://orcid.org/0000-0001-6912-7411
Beat KellerUniversity of Zurich, Department of Plant and Microbial Biology, Zollikerstrasse 107, 8008, Zurich, Switzerland. bkeller@botinst.uzh.ch.ORCID http://orcid.org/0000-0003-2379-9225
University of Zurich · CHCzech Academy of Sciences, Institute of Experimental Botany · CZKing Abdullah University of Science and Technology · SAMax Planck Institute for Developmental Biology · DEUniversity of Neuchâtel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plasma membrane-associated and intracellular proteins and protein complexes play a pivotal role in pathogen recognition and disease resistance signaling in plants and animals. The two predominant protein families perceiving plant pathogens are receptor-like kinases and nucleotide binding-leucine-rich repeat receptors (NLR), which often confer race-specific resistance. Leaf rust is one of the most prevalent and most devastating wheat diseases. Here, we clone the race-specific leaf rust resistance gene Lr14a from hexaploid wheat. The cloning of Lr14a is aided by the recently published genome assembly of ArinaLrFor, an Lr14a-containing wheat line. Lr14a encodes a membrane-localized protein containing twelve ankyrin (ANK) repeats and structural similarities to Ca

Indexed as

Ankyrin RepeatBasidiomycotaDisease ResistanceGene Expression Regulation, PlantGene PoolGene SilencingGenes, PlantHaplotypesMembrane ProteinsMutagenesisNicotianaPlant BreedingPlant DiseasesPlant ProteinsTriticumMembrane ProteinsPlant Proteins

Identifiers

PMID33574268
PMCPMC7878491
OpenAlexW3126239535

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.