Trial reportBMJ open2021
Neonatal hypothermia in Northern Uganda: a community-based cross-sectional study.
Trial report in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02605369 (SURVIVAL PLUSS), which is not on this map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
SURVIVAL PLUSS: Increasing Capacity for Mama-baby Survival in Post-conflict Uganda and South Sudan
Who cites it
12 citing papers in PubMed, 24 citations in OpenAlex.
- Prevalence and Factors Associated with Neonatal Hypothermia in Sub-Saharan Africa: Systematic Review and Meta-Analysis.Journal of clinical medicine · 2026Review
- Development and Validation of a Neonatal Hypothermia Prediction Model for In-Hospital Transport Using Machine Learning Algorithms: A Single-Center Retrospective Study.Journal of multidisciplinary healthcare · 2025Article
- Prevalence and determinants of neonatal hypothermia in a tertiary hospital, Gondar Ethiopia: a cross-sectional study.Scientific reports · 2024Article
- Clinical profiles, incidence and predictors of early neonatal mortality at Mbarara Regional Referral Hospital, south-western Uganda.BMC pediatrics · 2024Article
- Hypothermia in preterm infants admitted to low-resource neonatal units in northern Nigeria: an observational study of occurrence and risk factors.BMC pediatrics · 2024Observational
- Comparative study of neonatal hypothermia and associated factors among neonates in rural and urban areas of the Shebadino Woreda, Sidama region, Southern Ethiopia: a community-based comparative cross-sectional study.BMC public health · 2024Article
- Factors Influencing the Implementation of Infant Warming Devices Among Healthcare Workers in Malawian Hospitals.Global pediatric health · 2024Article
- Assessment of early neonatal practices to prevent hypothermia ; A comparative study.F1000Research · 2024Article
- Article
- Acceptability and feasibility of the BEMPU TempWatch for hypothermia monitoring in neonatal care in Ghana: a qualitative study of clinicians' perspectives.BMJ public health · 2023Article
- Use of access port covers in transport incubators to improve thermoregulation during neonatal transport.Scientific reports · 2023Article
- Admission Hypothermia and Neonatal Mortality in the Ethiopian Neonatal Network.Sage open pediatricsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo determine the prevalence, predictors and case fatality risk of hypothermia among neonates in Lira district, Northern Uganda.
settingThree subcounties of Lira district in Northern Uganda.
designThis was a community-based cross-sectional study nested in a cluster randomised controlled trial.
participantsMother-baby pairs enrolled in a cluster randomised controlled trial. An axillary temperature was taken during a home visit using a lithium battery-operated digital thermometer. PRIMARY AND SECONDARY OUTCOMES: The primary outcome measure was the prevalence of hypothermia. Hypothermia was defined as mild if the axillary temperature was 36.0°C to <36.5°C, moderate if the temperature was 32.0°C to <36.0°C and severe hypothermia if the temperature was <32.0°C. The secondary outcome measure was the case fatality risk of neonatal hypothermia. Predictors of moderate to severe hypothermia were determined using a generalised estimating equation model for the Poisson family.
resultsWe recruited 1330 neonates. The prevalence of hypothermia (<36.5°C) was 678/1330 (51.0%, 95% CI 46.9 to 55.1). Overall, 32% (429/1330), 95% CI 29.5 to 35.2 had mild hypothermia, whereas 18.7% (249/1330), 95% CI 15.8 to 22.0 had moderate hypothermia. None had severe hypothermia. At multivariable analysis, predictors of neonatal hypothermia included: home birth (adjusted prevalence ratio, aPR, 1.9, 95% CI 1.4 to 2.6); low birth weight (aPR 1.7, 95% CI 1.3 to 2.3) and delayed breastfeeding initiation (aPR 1.2, 95% CI 1.0 to 1.5). The case fatality risk ratio of hypothermic compared with normothermic neonates was 2.0 (95% CI 0.60 to 6.9).
conclusionThe prevalence of neonatal hypothermia was very high, demonstrating that communities in tropical climates should not ignore neonatal hypothermia. Interventions designed to address neonatal hypothermia should consider ways of reaching neonates born at home and those with low birth weight. The promotion of early breastfeeding initiation and skin-to-skin care could reduce the risk of neonatal hypothermia. TRIAL REGISTRATION NUMBER: ClinicalTrial.gov as NCT02605369.
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