ArticleAJNR. American journal of neuroradiology2021
Altered Processing of Complex Visual Stimuli in Patients with Postconcussive Visual Motion Sensitivity.
Article in AJNR. American journal of neuroradiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 15 citations in OpenAlex.
- In People With Subacute Mild Traumatic Brain Injury, Earlier Physical Therapy Improved Symptoms at a Faster Rate Than Later Physical Therapy: Randomized Controlled Trial.Physical therapy · 2025Trial
- A Diagnostic Framework for the Management of Post-Concussion Visually Induced Dizziness: Recognising Postural and Visuoperceptual Subtypes Using an Optokinetic Balance Assessment.Brain sciences · 2026Article
- Self-reported dizziness, balance, and multisensory impairment following mild traumatic brain injury: an exploratory study.Journal of the Royal Society of New Zealand · 2025Article
- Vestibular dysfunction leads to cognitive impairments: State of knowledge in the field and clinical perspectives (Review).International journal of molecular medicine · 2024Review
- Symptoms and Central Sensory Integration in People With Chronic mTBI: Clinical Implications.Military medicine · 2023Article
- Eagle-449: A volumetric, whole-brain compilation of brain atlases for vestibular functional MRI research.Scientific data · 2023Article
- The human vestibular cortex: functional anatomy of OP2, its connectivity and the effect of vestibular disease.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Mild-to-Moderate Traumatic Brain Injury: A Review with Focus on the Visual System.Neurology international · 2022Review
- The "vestibular neuromatrix": A proposed, expanded vestibular network from graph theory in post-concussive vestibular dysfunction.Human brain mapping · 2022Article
- Patterns of vestibular dysfunction in chronic traumatic brain injury.Frontiers in neurology · 2022Article
- Multisensory integration and white matter pathology: Contributions to cognitive dysfunction.Frontiers in neurology · 2022Review
- Central sensorimotor integration assessment reveals deficits in standing balance control in people with chronic mild traumatic brain injury.Frontiers in neurology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeVestibular symptoms are common after concussion. Vestibular Ocular Motor Screening identifies vestibular impairment, including postconcussive visual motion sensitivity, though the underlying functional brain alterations are not defined. We hypothesized that alterations in multisensory processing are responsible for postconcussive visual motion sensitivity, are detectable on fMRI, and correlate with symptom severity. MATERIALS AND
methodsTwelve patients with subacute postconcussive visual motion sensitivity and 10 healthy control subjects underwent vestibular testing and a novel fMRI visual-vestibular paradigm including 30-second "neutral" or "provocative" videos. The presence of symptoms/intensity was rated immediately after each video. fMRI group-level analysis was performed for a "provocative-neutral" condition.
resultsSubjects with postconcussive visual motion sensitivity had significantly more Vestibular Ocular Motor Screening abnormalities and increased symptoms while viewing provocative videos. While robust mean activation in the primary and secondary visual areas, the parietal lobe, parietoinsular vestibular cortex, and cingulate gyrus was seen in both groups, selective increased activation was seen in subjects with postconcussive visual motion sensitivity in the primary vestibular/adjacent cortex and inferior frontal gyrus, which are putative multisensory visual-vestibular processing centers. Moderate-to-strong correlations were found between Vestibular Ocular Motor Screening scores and fMRI activation in the left frontal eye field, left middle temporal visual area, and right posterior hippocampus.
conclusionsIncreased fMRI brain activation in visual-vestibular multisensory processing regions is selectively seen in patients with postconcussive visual motion sensitivity and is correlated with Vestibular Ocular Motor Screening symptom severity, suggesting that increased visual input weighting into the vestibular network may underlie postconcussive visual motion sensitivity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.