Evidence map›Paper›PMID 33574095›Full record

ArticleJournal of investigative medicine : the official publication of the American Federation for Clinical Research2021

Assessing bronchodilator response by changes in per cent predicted forced expiratory volume in one second.

Octavian C Ioachimescu, Jose A Ramos, Michael Hoffman, Kevin McCarthy, James K Stoller

Open access · hybridAbstract read
In one paragraph

Article in Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Small Airways Response to Bronchodilators in Adults with Asthma or COPD: A Systematic Review.International journal of chronic obstructive pulmonary disease
    Pooled it
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Octavian C IoachimescuMedicine, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Emory University School of Medicine, Atlanta, Georgia, USA oioac@yahoo.com.ORCID 0000-0001-9047-6894
Jose A RamosRespiratory Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Michael HoffmanRespiratory Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Kevin McCarthyRespiratory Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
James K StollerRespiratory Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Cleveland Clinic · USEmory University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In pulmonary function testing by spirometry, bronchodilator responsiveness (BDR) evaluates the degree of volume and airflow improvement in response to an inhaled short-acting bronchodilator (BD). The traditional, binary categorization (present vs absent BDR) has multiple pitfalls and limitations. To overcome these limitations, a novel classification that defines five categories (negative, minimal, mild, moderate and marked BDR), and based on % and absolute changes in forced expiratory volume in 1 s (FEV

Indexed as

Bronchodilator AgentsForced Expiratory VolumePulmonary Disease, Chronic ObstructiveHumansSpirometryVital CapacityBronchodilator Agentschronic obstructivepulmonary diseaserespiration disordersrespiratory physiological phenomenarespiratory system

Identifiers

PMID33574095
PMCPMC8223640
OpenAlexW3127118763

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.