Evidence map›Paper›PMID 33574074›Full record

ArticleThe European respiratory journal2021

Point-of-care lung ultrasound assessment for risk stratification and therapy guiding in COVID-19 patients: a prospective noninterventional study.

Jorge Rubio-Gracia, Ignacio Giménez-López, Vanesa Garcés-Horna, Daniel López-Delgado, Jose Luis Sierra-Monzón, Luis Martínez-Lostao, Claudia Josa-Laorden, Fernando Ruiz-Laiglesia, Juan Ignacio Pérez-Calvo, Silvia Crespo-Aznarez and 5 more

Open access · hybridAbstract read
In one paragraph

Article in The European respiratory journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 3 pooled it
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 3 syntheses or guidelines pooled it, 53 citations in OpenAlex.

  1. Pooled it
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  3. Association of Lung Ultrasound Score with Mortality and Severity of COVID-19: A Meta-Analysis and Trial Sequential Analysis.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Jorge Rubio-GraciaInternal Medicine Dept, Clinical Hospital "Lozano Blesa", Zaragoza, Spain.
Ignacio Giménez-LópezAragon Health Research Institute, Zaragoza, Spain.
Vanesa Garcés-HornaInternal Medicine Dept, Clinical Hospital "Lozano Blesa", Zaragoza, Spain.
Daniel López-DelgadoInternal Medicine Dept, Clinical Hospital "Lozano Blesa", Zaragoza, Spain.
Jose Luis Sierra-MonzónAragon Health Research Institute, Zaragoza, Spain.
Luis Martínez-LostaoAragon Health Research Institute, Zaragoza, Spain.
Claudia Josa-LaordenInternal Medicine Dept, Clinical Hospital "Lozano Blesa", Zaragoza, Spain.
Fernando Ruiz-LaiglesiaInternal Medicine Dept, Clinical Hospital "Lozano Blesa", Zaragoza, Spain.
Juan Ignacio Pérez-CalvoInternal Medicine Dept, Clinical Hospital "Lozano Blesa", Zaragoza, Spain.
Silvia Crespo-AznarezInternal Medicine Dept, Clinical Hospital "Lozano Blesa", Zaragoza, Spain.
Javier García-LafuenteInternal Medicine Dept, Clinical Hospital "Lozano Blesa", Zaragoza, Spain.
Natacha Peña FresnedaAragon Health Research Institute, Zaragoza, Spain.
Beatriz Amores ArriagaInternal Medicine Dept, Clinical Hospital "Lozano Blesa", Zaragoza, Spain.
Borja Gracia-TelloInternal Medicine Dept, Clinical Hospital "Lozano Blesa", Zaragoza, Spain.
Marta Sánchez-MartelesInternal Medicine Dept, Clinical Hospital "Lozano Blesa", Zaragoza, Spain.
Hospital Clínico Universitario Lozano Blesa · ESInstituto de Investigación Sanitaria Aragón · ESUniversidad de Zaragoza · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLung ultrasound is feasible for assessing lung injury caused by coronavirus disease 2019 (COVID-19). However, the prognostic meaning and time-line changes of lung injury assessed by lung ultrasound in COVID-19 hospitalised patients are unknown.

methodsProspective cohort study designed to analyse prognostic value of lung ultrasound in COVID-19 patients by using a quantitative scale (lung ultrasound Zaragoza (LUZ)-score) during the first 72 h after admission. The primary end-point was in-hospital death and/or admission to the intensive care unit. Total length of hospital stay, increase of oxygen flow and escalation of medical treatment during the first 72 h were secondary end-points.

results130 patients were included in the final analysis; mean±sd age was 56.7±13.5 years. Median (interquartile range) time from the beginning of symptoms to admission was 6 (4-9) days. Lung injury assessed by LUZ-score did not differ during the first 72 h (21 (16-26) points at admission

conclusionsLUZ-score is an easy, simple and fast point-of-care ultrasound tool to identify patients with severe lung injury due to COVID-19, upon admission. Baseline score is predictive of severity along the whole period of hospitalisation. The score facilitates early implementation or intensification of treatment for COVID-19 infection. LUZ-score may be combined with clinical variables (as estimated by PAFI) to further refine risk stratification.

Indexed as

COVID-19Point-of-Care SystemsAdultAgedHospital MortalityHumansLungMiddle AgedProspective StudiesRisk AssessmentSARS-CoV-2

Identifiers

PMID33574074
PMCPMC7877323
OpenAlexW3127742801

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.