Evidence map›Paper›PMID 33573928›Full record

Observational studyJournal of cardiothoracic and vascular anesthesia2021

Six-Month Survival After Extracorporeal Membrane Oxygenation for Severe COVID-19.

Fausto Biancari, Giovanni Mariscalco, Magnus Dalén, Nicla Settembre, Henryk Welp, Andrea Perrotti, Karsten Wiebe, Enrico Leo, Antonio Loforte, Sidney Chocron and 14 more

Registry-linked trialOpen access · hybridAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Journal of cardiothoracic and vascular anesthesia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04383678 (Outcome of COVID-19 Patients After Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome), which is not on this map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04383678 completednot on this map

Outcome of COVID-19 Patients After Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome: A Multicenter European Study

TypeobservationalSponsorHelsinki University Central HospitalRan2020 to 2021Enrolled132ConditionsCOVID-19, Extracorporeal Membrane Oxygenation Complication, Acute Respiratory Distress SyndromeArmsExtracorporeal membrane oxygenation
3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 67 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. VV-ECMO in critical COVID-19 obese patients: a cohort study.Journal of anesthesia, analgesia and critical care · 2024
    Article
  6. Article
  7. Article
  8. Observational
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

24 authors at 12 institutions in 6 countries.

Fausto BiancariHeart and Lung Center, Helsinki University Hospital, Helsinki, Finland; Research Unit of Surgery, Anesthesia and Critical Care, University of Oulu, Oulu, Finland; Department of Surgery, University of Turku, Turku, Finland. Electronic address: faustobiancari@yahoo.it.
Giovanni MariscalcoDepartment of Intensive Care Medicine and Cardiac Surgery, Glenfield Hospital, University Hospitals of Leicester, Leicester, UK.
Magnus DalénDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Department of Cardiothoracic Surgery, Karolinska University Hospital, Stockholm, Sweden.
Nicla SettembreDepartment of Vascular and Endovascular Surgery, Nancy University Hospital, University of Lorraine, Nancy, France.
Henryk WelpDepartment of Cardiothoracic Surgery, Münster University Hospital, Münster, Germany.
Andrea PerrottiDepartment of Thoracic and Cardio-Vascular Surgery, University Hospital Jean Minjoz, Besançon, France.
Karsten WiebeDepartment of Cardiothoracic Surgery, Münster University Hospital, Münster, Germany.
Enrico LeoDivision of Vascular Surgery, A. Manzoni Hospital, Lecco, Italy.
Antonio LoforteDepartment of Cardiothoracic, Transplantation and Vascular Surgery, S. Orsola Hospital, University of Bologna, Bologna, Italy.
Sidney ChocronDepartment of Thoracic and Cardio-Vascular Surgery, University Hospital Jean Minjoz, Besançon, France.
Davide PaciniDepartment of Cardiothoracic, Transplantation and Vascular Surgery, S. Orsola Hospital, University of Bologna, Bologna, Italy.
Tatu JuvonenHeart and Lung Center, Helsinki University Hospital, Helsinki, Finland; Research Unit of Surgery, Anesthesia and Critical Care, University of Oulu, Oulu, Finland.
L Mikael BromanDepartment of Physiology and Pharmacology, Karolinska Institutet, ECMO Centre Karolinska, Karolinska University Hospital, Stockholm, Sweden.
Dario Di PernaDivision of Cardiothoracic and Vascular Surgery, Robert Debré University Hospital, Université Reims Champagne-Ardenne, Reims, France.
Hakeem YusuffDepartment of Intensive Care Medicine and Cardiac Surgery, Glenfield Hospital, University Hospitals of Leicester, Leicester, UK.
Chris HarveyDepartment of Intensive Care Medicine and Cardiac Surgery, Glenfield Hospital, University Hospitals of Leicester, Leicester, UK.
Nicolas MongardonService d'Anesthésie-réanimation Chirurgicale, Hôpital Henri-Mondor, Assistance Publique - Hôpitaux de Paris, Créteil, France.
Juan P MaureiraDepartment of Cardiovascular Surgery and Heart Transplantation, Nancy University Hospital, University of Lorraine, Nancy, France.
Bruno LevyMedical Intensive Care Unit Brabois, Nancy University Hospital, University of Lorraine, Nancy, France.
Lars FalkDepartment of Physiology and Pharmacology, Karolinska Institutet, ECMO Centre Karolinska, Karolinska University Hospital, Stockholm, Sweden.
Vito G RuggieriDivision of Cardiothoracic and Vascular Surgery, Robert Debré University Hospital, Université Reims Champagne-Ardenne, Reims, France.
Svante ZipfelHeart Center, Hamburg University Hospital, Hamburg, Germany.
Thierry FolliguetService de Chirurgie Thoracique et Cardio-vasculaire, Hôpital Henri-Mondor, Assistance Publique - Hôpitaux de Paris, Créteil, France.
Antonio FioreService de Chirurgie Thoracique et Cardio-vasculaire, Hôpital Henri-Mondor, Assistance Publique - Hôpitaux de Paris, Créteil, France.
Assistance Publique – Hôpitaux de Paris · FRGlenfield Hospital · GBKarolinska University Hospital · SEUniversité de Lorraine · FRCentre Hospitalier Universitaire de Besançon · FRUniversité de Reims Champagne-Ardenne · FRUniversity Hospital Münster · DEUniversity of Bologna · ITAlessandro Manzoni Hospital · ITOulu University Hospital · FIUniversität Hamburg · DEUniversity of Turku · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe authors evaluated the outcome of adult patients with coronavirus disease 2019 (COVID-19)-related acute respiratory distress syndrome (ARDS) requiring the use of extracorporeal membrane oxygenation (ECMO).

designMulticenter retrospective, observational study.

settingTen tertiary referral university and community hospitals.

participantsPatients with confirmed severe COVID-19-related ARDS.

interventionsVenovenous or venoarterial ECMO. MEASUREMENTS AND MAIN

resultsOne hundred thirty-two patients (mean age 51.1 ± 9.7 years, female 17.4%) were treated with ECMO for confirmed severe COVID-19-related ARDS. Before ECMO, the mean Sequential Organ Failure Assessment score was 10.1 ± 4.4, mean pH was 7.23 ± 0.09, and mean PaO

conclusionsThe present findings suggested that about half of adult patients with severe COVID-19-related ARDS can be managed successfully with ECMO with sustained results at six months. Decreased arterial pH before ECMO was associated significantly with early mortality. Therefore, the authors hypothesized that initiation of ECMO therapy before severe metabolic derangements subset may improve survival rates significantly in these patients. These results should be viewed in the light of a strict patient selection policy and may not be replicated in patients with advanced age or multiple comorbidities. CLINICAL

trial registrationidentifier, NCT04383678.

Indexed as

COVID-19Extracorporeal Membrane OxygenationRespiratory Distress SyndromeAdultFemaleHumansMiddle AgedRetrospective StudiesSARS-CoV-2acute respiratory distress syndromeARDScoronavirus disease 2019COVID-19ECLSECMOextracorporeal membrane oxygenation

Identifiers

PMID33573928
PMCPMC7816613
OpenAlexW3124281496

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.