Evidence map›Paper›PMID 33573648›Full record

ArticleEnvironmental health : a global access science source2021

Residential exposure to air pollution and access to neighborhood greenspace in relation to hair cortisol concentrations during the second and third trimester of pregnancy.

Veerle Josefa Verheyen, Sylvie Remy, Nathalie Lambrechts, Eva Govarts, Ann Colles, Lien Poelmans, Els Verachtert, Wouter Lefebvre, Pieter Monsieurs, Charlotte Vanpoucke and 4 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Environmental health : a global access science source, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02592005 (Impact of Particulate Matter on Mothers and Babies in Antwerp), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02592005 unknown statusnot on this map

Impact of Particulate Matter on Mothers and Babies in Antwerp (IPANEMA), a Prospective Cohort Study on the Impact of Pollutants and Particulate Matter in Pregnancy: Methodology and Design

TypeobservationalSponsorUniversiteit AntwerpenRan2015 to 2018Enrolled200ConditionsPregnancy, PreeclampsiaArmsamount of fine dust and other environmental exposure
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Observational
  5. Article
  6. PMEnvironmental health : a global access science source · 2025
    Article
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  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Ambient PMInhalation toxicology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 3 countries.

Veerle Josefa VerheyenFlemish Institute for Technological Research (VITO), Mol, Belgium. veerle.verheyen@vito.be.ORCID 0000-0002-5262-5665
Sylvie RemyFlemish Institute for Technological Research (VITO), Mol, Belgium.
Nathalie LambrechtsFlemish Institute for Technological Research (VITO), Mol, Belgium.
Eva GovartsFlemish Institute for Technological Research (VITO), Mol, Belgium.
Ann CollesFlemish Institute for Technological Research (VITO), Mol, Belgium.
Lien PoelmansFlemish Institute for Technological Research (VITO), Mol, Belgium.
Els VerachtertFlemish Institute for Technological Research (VITO), Mol, Belgium.
Wouter LefebvreFlemish Institute for Technological Research (VITO), Mol, Belgium.
Pieter MonsieursFlemish Institute for Technological Research (VITO), Mol, Belgium.
Charlotte VanpouckeBelgian Interregional Environment Agency, Brussels, Belgium.
Flemming NielsenThe Department of Public Health, University of Southern Denmark, Odense, Denmark.
Lena Van den EedenDepartment of Obstetrics and Gynecology, Antwerp University Hospital, Antwerp, Belgium.
Yves JacquemynDepartment of Obstetrics and Gynecology, Antwerp University Hospital, Antwerp, Belgium.
Greet SchoetersFlemish Institute for Technological Research (VITO), Mol, Belgium.
Flemish Institute for Technological Research · BEUniversity of Antwerp · BEBelgian Development Agency · BEThomas More University · USUniversity of Southern Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExposure to air pollution during pregnancy has been associated with adverse pregnancy outcomes in studies worldwide, other studies have described beneficial effects of residential greenspace on pregnancy outcomes. The biological mechanisms that underlie these associations are incompletely understood. A biological stress response, which implies release of cortisol, may underlie associations of air pollution exposure and access to neighborhood greenspaces with health.

methodsWe explored residential exposure to air pollution and residential access to neighborhood greenspaces in relation to hair cortisol concentrations of participants in a prospective pregnancy cohort study in Flanders, Belgium. Hair samples were collected at the end of the second pregnancy trimester (n = 133) and shortly after delivery (n = 81). Cortisol concentrations were measured in 3-cm scalp-near hair sections, to reflect second and third pregnancy trimester cortisol secretion. We estimated long-term (3 months before sampling) residential exposure to fine particulate matter (PM

resultsThree-month mean residential NO

conclusionsOur findings suggest a positive association between long-term residential exposure to air pollution and biological stress during pregnancy, residential access to neighborhood greenspaces may moderate the association. Further research is needed to confirm our results.

trial registrationThe IPANEMA study is registered under number  NCT02592005 at clinicaltrials.gov .

Indexed as

Parks, RecreationalAdultAir PollutantsAir PollutionBelgiumEnvironmental ExposureFemaleHairHumansHydrocortisonePregnancyPregnancy Trimester, SecondPregnancy Trimester, ThirdProspective StudiesResidence CharacteristicsStress, PsychologicalAir PollutantsHydrocortisoneVehicle EmissionsAir pollutionHair cortisol concentrationsLonger-term biological stressNeighborhood greenspacePregnancyProximity to major roads

Identifiers

PMID33573648
PMCPMC7879652
OpenAlexW3128488011

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.