ArticleBMC infectious diseases2021
Maximal diameter of liver abscess independently predicts prolonged hospitalization and poor prognosis in patients with pyogenic liver abscess.
Article in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
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29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Prognostic Factors for Mortality in Patients with Pyogenic Liver Abscess: A Systematic Review and Meta-Analysis.International journal of medical sciences · 2026Pooled it
- Pooled it
- Association between prognostic nutritional index and clinical outcomes in patients with pyogenic liver abscess: a retrospective multicenter study.BMC infectious diseases · 2026Article
- When Clinical Improvement Does Not Reflect Radiological Response: A Culture-Negative Giant Pyogenic Liver Abscess.Healthcare (Basel, Switzerland) · 2026Article
- Feasibility analysis of ultrasound-guided percutaneous catheter drainage for pyogenic liver abscess in non-liquefied stages.World journal of gastrointestinal surgery · 2026Article
- A machine learning-based online prediction model for recurrence risk in patients withFrontiers in cellular and infection microbiology · 2026Article
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- Article
- Development and validation of a nomogram for predicting antibiotic treatment duration in patients with liver abscess complicated by diabetes.Scientific reports · 2025Article
- Clinical characteristics, pathogenic bacteria, and risk factors for different locations of pyogenic liver abscesses: a 10-year analysis.Frontiers in cellular and infection microbiology · 2025Article
- A rare case ofIDCases · 2025Article
- Analysis of clinical characteristics of elderly patients with blood culture-positive bacterial liver abscess.Frontiers in medicine · 2025Article
- Development of a nomogram to assess thromboembolic risk in patients with liver abscesses.Scientific reports · 2024Article
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- Article
- Tumor complete response and pyogenic liver abscess secondary to concurrent microwave ablation plus atezolizumab and bevacizumab in liver cancer: a case report.Journal of gastrointestinal oncology · 2024Article
- Clinical characteristics and management of liver abscess in The Gambia, a resource-limited country.BMC gastroenterology · 2024Article
- Antibiotic treatment durations for pyogenic liver abscesses: A systematic review.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2023Article
- Risk factors indicating the need for surgical therapy in patients with pyogenic liver abscesses.Langenbeck's archives of surgery · 2023Article
- Clinical significance of dynamic variation of low cholesterol and its prognostic value in patients with pyogenic liver abscesses: a retrospective study.BMC infectious diseases · 2023Article
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Authors and funding
12 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimsThis study aimed to investigate the factors associated with prolonged hospital stay and in-hospital mortality in patients with pyogenic liver abscess.
methodsWe retrospectively reviewed data from patients with pyogenic liver abscess who were admitted between 2005 and 2018 at three tertiary hospitals in Jeonbuk province, South Korea. Prolonged hospital stay was defined as a duration of hospital admission of more than 21 days.
resultsA total of 648 patients (406 men and 242 women) diagnosed with pyogenic liver abscess were enrolled in the study. The mean maximal diameter of the liver abscess was 5.4 ± 2.6 cm, and 74.9% of the lesions were single. The three groups were divided according to the maximal diameter of the abscess. Laboratory parameters indicated a more severe inflammatory state and higher incidence of complications and extrahepatic manifestations with increasing abscess size. Rates of percutaneous catheter drainage (PCD) insertion, multiple PCD drainage, and salvage procedures as well as duration of drainage were also higher in the large liver abscess group. Of note, the duration of hospitalization and in-hospital mortality were significantly higher in the large hepatic abscess group. A multivariate analysis revealed that underlying diabetes mellitus, hypoalbuminemia, high baseline high-sensitivity C-reactive protein (hs-CRP) and procalcitonin levels, and large maximal abscess diameter were independent factors associated with prolonged hospital stay. Regarding in-hospital mortality, acute kidney injury at admission and maximal diameter of the abscess were independent factors associated with in-hospital mortality.
conclusionsA large maximal diameter of the liver abscess at admission indicated prolonged hospitalization and poor prognosis. More aggressive treatment strategies with careful monitoring are warranted in patients with large liver abscesses.
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