Evidence map›Paper›PMID 33573445›Full record

ArticleJournal of biomaterials applications2021

Alternative radiopacifiers for polymethyl methacrylate bone cements: Silane-treated anatase titanium dioxide and yttria-stabilised zirconium dioxide.

Wayne Nishio Ayre, Nicole Scully, Carole Elford, Bronwen Aj Evans, Wendy Rowe, Jeff Rowlands, Ravi Mitha, Paul Malpas, Panagiota Manti, Cathy Holt and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of biomaterials applications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Enhanced bone cement for fixation of prosthetic joint utilizing nanoparticles.Journal of materials science. Materials in medicine · 2025
    Article
  3. Article
  4. Review
  5. TiOOdontology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Wayne Nishio AyreSchool of Dentistry, Cardiff University, Cardiff, UK.ORCID 0000-0003-2405-1876
Nicole ScullySchool of Medicine, Cardiff University, Cardiff, UK.
Carole ElfordSchool of Medicine, Cardiff University, Cardiff, UK.
Bronwen Aj EvansSchool of Medicine, Cardiff University, Cardiff, UK.
Wendy RoweSchool of Dentistry, Cardiff University, Cardiff, UK.
Jeff RowlandsSchool of Engineering, Cardiff University, Cardiff, UK.
Ravi MithaSchool of Engineering, Cardiff University, Cardiff, UK.
Paul MalpasSchool of Engineering, Cardiff University, Cardiff, UK.
Panagiota MantiSchool of Environment, Ionian University, Zakynthos, Greece.
Cathy HoltSchool of Engineering, Cardiff University, Cardiff, UK.
Rhidian Morgan-JonesDepartment of Trauma & Orthopaedics, Cardiff & Vale University Health Board, Cardiff, UK.
James C BirchallSchool of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff, UK.
Stephen P DenyerSchool of Pharmacy and Biomolecular Sciences, University of Brighton, Brighton, UK.
Sam L EvansSchool of Engineering, Cardiff University, Cardiff, UK.
Cardiff University · GBCardiff and Vale University Health Board · GBIonian University · GRUniversity of Brighton · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Poly (methyl methacrylate) (PMMA) bone cement is widely used for anchoring joint arthroplasties. In cement brands approved for these procedures, micron-sized particles (usually barium sulphate, BaSO

Indexed as

AnimalsBarium SulfateBone CementsCell AdhesionCell LineCell SurvivalCoated Materials, BiocompatibleCompressive StrengthMiceParticle SizePolymethyl MethacrylateSilanesStress, MechanicalTitaniumYttriumZirconiumBarium SulfateBone CementsCoated Materials, BiocompatiblePolymethyl MethacrylateSilanesTitaniumtitanium dioxideyttriaYttriumZirconiumzirconium oxidebiocompatibilitybone cementmechanicalPMMAradiopacifiersilanetoxicity

Identifiers

PMID33573445
PMCPMC8058833
OpenAlexW3128495924

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.