Evidence map›Paper›PMID 33573428›Full record

ArticleRNA biology2021

Universal functions of the σ finger in alternative σ factors during transcription initiation by bacterial RNA polymerase.

Anastasiya Oguienko, Ivan Petushkov, Danil Pupov, Daria Esyunina, Andrey Kulbachinskiy

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RNA biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Anastasiya OguienkoInstitute of Molecular Genetics, NRC "Kurchatov Institute", Moscow, Russia.
Ivan PetushkovInstitute of Molecular Genetics, NRC "Kurchatov Institute", Moscow, Russia.
Danil PupovInstitute of Molecular Genetics, NRC "Kurchatov Institute", Moscow, Russia.
Daria EsyuninaInstitute of Molecular Genetics, NRC "Kurchatov Institute", Moscow, Russia.
Andrey KulbachinskiyInstitute of Molecular Genetics, NRC "Kurchatov Institute", Moscow, Russia.
Institute of Molecular Genetics · RUKurchatov Institute · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The bacterial σ factor plays the central role in promoter recognition by RNA polymerase (RNAP). The primary σ factor, involved in transcription of housekeeping genes, was also shown to participate in the initiation of RNA synthesis and promoter escape by RNAP. In the open promoter complex, the σ finger formed by σ region 3.2 directly interacts with the template DNA strand upstream of the transcription start site. Here, we analysed the role of the σ finger in transcription initiation by four alternative σ factors in

Indexed as

Gene Expression Regulation, BacterialTranscription Initiation SiteDNA-Directed RNA PolymerasesEscherichia coliEscherichia coli ProteinsGuanosine TetraphosphatePromoter Regions, GeneticRNA, BacterialSigma FactorTranscription, GeneticdksA protein, E coliDNA-Directed RNA PolymerasesEscherichia coli ProteinsGuanosine TetraphosphateRNA, BacterialSigma Factoralternative σ factorsDksAECF σ factorsppGpppromoter complex stabilityRNA polymeraseσ finger

Identifiers

PMID33573428
PMCPMC8583087
OpenAlexW3127823330

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.