Evidence map›Paper›PMID 33573359›Full record

ArticlePolymers2021

Synthesis of Multi-Functional Nano-Vectors for Target-Specific Drug Delivery.

Tzu-Chien Wu, Pei-Yuan Lee, Chiao-Ling Lai, Chian-Hui Lai

Abstract read
In one paragraph

Article in Polymers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tzu-Chien WuGraduate Institute of Biomedical Engineering, National Chung Hsing University, Taichung 402, Taiwan.
Pei-Yuan LeeOrthopedic Department, Show Chwan Memorial Hospital, Changhua 500, Taiwan.
Chiao-Ling LaiGraduate Institute of Biomedical Engineering, National Chung Hsing University, Taichung 402, Taiwan.
Chian-Hui LaiGraduate Institute of Biomedical Engineering, National Chung Hsing University, Taichung 402, Taiwan.ORCID 0000-0002-2697-4845

Funding

Ministry of Science and Technology, Taiwan MOST 109-2113-M-005-002-
6 · The paper itself

Abstract

Magnetic nanoparticles have gained attention in cancer therapy due to their non-toxic properties and high bio-compatibility. In this report, we synthesize a dual-responsive magnetic nanoparticle (MNP) that is sensitive to subtle pH and temperature change as in the tumor microenvironment. Thus, the functional doxorubicin (DOX)-loaded MNP (DOX-PNIPAM-PMAA@Fe

Indexed as

drug deliverydual-responsive nano-carrierenhanced permeability and retention effect (EPR effect)magnetic nanoparticle (MNP)tumor microenvironment (TME)

Identifiers

PMID33573359
PMCPMC7866831

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.