Evidence map›Paper›PMID 33573279›Full record

ArticleJournal of personalized medicine2021

rs6837671A>G in

Said El Shamieh, Ali Salami, Mirna Fawaz, Rania Jounblat, Mirna Waked, Rajaa Fakhoury

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Said El ShamiehDepartment of Medical Laboratory Technology, Faculty of Health Sciences, Beirut Arab University, Beirut P.O. Box 115020, Lebanon.ORCID 0000-0002-8522-0445
Ali SalamiRammal Hassan Rammal Research Laboratory, PhyToxE Research Group, Faculty of Sciences, Lebanese University, Nabatieh P.O. Box 6573/14, Lebanon.ORCID 0000-0003-3343-4035
Mirna FawazDepartment of Nursing, Faculty of Health Sciences, Beirut Arab University, Beirut P.O. Box 115020, Lebanon.
Rania JounblatDepartment of Life and Earth Sciences, Faculty of Sciences II, Lebanese University, Fanar P.O. Box 26110217, Lebanon.
Mirna WakedDepartment of Pulmonology, St George Hospital University Medical Center, Achrafieh Beirut, P.O. Box 166 378, Lebanon.
Rajaa FakhouryDepartment of Medical Laboratory Technology, Faculty of Health Sciences, Beirut Arab University, Beirut P.O. Box 115020, Lebanon.
Beirut Arab University · LBLebanese University · LBUniversity of Balamand · LB

Funding

Beirut Arab University 2424
6 · The paper itself

Abstract

(1) Background and objectives: Chronic obstructive pulmonary disease (COPD) is a leading cause of mortality throughout the world. In addition to genetics, increasing evidence suggests that Vitamin D (VitD) might be involved in different pathogenic mechanisms in COPD. Furthermore, the prevalence of VitD insufficiency is exceptionally high in COPD patients and increases with the severity. Based on the above, we first tested the relation between the top 10 single nucleotide polymorphisms from genome-wide association studies and the risk of COPD. Then, we investigated whether VitD levels might also have a role in COPD. A meta-analysis followed, combining our participants with previously published European and non-European populations (15,716 cases and 48,107 controls). (2) Methods: 631 Lebanese participants were recruited, of which ~28% were affected with COPD. Demographic and clinical data were collected, and DNA was genotyped using Kompetitive allele-specific PCR (KASPT

Indexed as

chronic obstructive pulmonary diseaseinteractionmeta-analysissingle nucleotide polymorphismvitamin D

Identifiers

PMID33573279
PMCPMC7912529
OpenAlexW3126618942

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.