Evidence map›Paper›PMID 33573264›Full record

ArticleInternational journal of environmental research and public health2021

Gestational Exposure to Phthalates and Social Responsiveness Scores in Children Using Quantile Regression: The EARLI and HOME Studies.

Marisa A Patti, Craig Newschaffer, Melissa Eliot, Ghassan B Hamra, Aimin Chen, Lisa A Croen, M Daniele Fallin, Irva Hertz-Picciotto, Geetika Kalloo, Jane C Khoury and 4 more

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Marisa A PattiDepartment of Epidemiology, Brown University, Providence, RI 02903, USA.ORCID 0000-0003-1113-3207
Craig NewschafferA.J. Drexel Autism Institute, Drexel University, Philadelphia, PA 19104, USA.
Melissa EliotDepartment of Epidemiology, Brown University, Providence, RI 02903, USA.
Ghassan B HamraDepartment of Epidemiology, Johns Hopkins University, Baltimore, MD 21205, USA.
Aimin ChenDepartment of Biostatistics Epidemiology and Informatics, University of Pennsylvania, Philadelphia, PA 19104, USA.
Lisa A CroenDivision of Research, Kaiser Permanente Northern California, Oakland, CA 94612, USA.
M Daniele FallinDepartment of Mental Health, Johns Hopkins University, Baltimore, MD 21205, USA.
Irva Hertz-PicciottoDepartment of Public Health Sciences, University of California, Davis, CA 95616, USA.
Geetika KallooHealthCore Inc., Wilmington, DE 19801, USA.
Jane C KhouryDivision of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45267, USA.ORCID 0000-0002-8064-6404
Bruce P LanphearFaculty of Health Sciences, Simon Fraser University, Vancouver, BC, Canada.
Kristen LyallA.J. Drexel Autism Institute, Drexel University, Philadelphia, PA 19104, USA.
Kimberly YoltonDepartment of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA.
Joseph M BraunDepartment of Epidemiology, Brown University, Providence, RI 02903, USA.ORCID 0000-0002-5239-3235

Funding

Translational Research Support CoreP30ES013508 · NIEHS · UNIVERSITY OF PENNSYLVANIA · PI Trevor M Penning · 2006 to 2026
$35.3M
Early Autism Risk Longitudinal Investigation (EARLI) NetworkR01ES016443 · NIEHS · DREXEL UNIVERSITY · PI NEWSCHAFFER, CRAIG J · 2008 to 2013
$15.6M
A Community-Based Trial to Prevent Lead Poisoning and InjuriesR01ES014575 · NIEHS · CINCINNATI CHILDRENS HOSP MED CTR · PI YOLTON, KIMBERLY · 2007 to 2011
$2.9M
Longitudinal study of exposure to PBDEs and PFCs and child neurobehaviorR01ES020349 · NIEHS · UNIVERSITY OF CINCINNATI · PI CHEN, AIMIN, LANPHEAR, BRUCE P · 2011 to 2015
$2.9M
Endocrine Disrupting Chemicals, Thyroid Hormones, and Child NeurobehaviorR01ES024381 · NIEHS · BROWN UNIVERSITY · PI BRAUN, JOSEPH M · 2015 to 2018
$2.4M
Prenatal Exposure to Endocrine Disrupting Chemical Mixtures and ASD RiskR01ES026903 · NIEHS · PENNSYLVANIA STATE UNIVERSITY, THE · PI NEWSCHAFFER, CRAIG J · 2017 to 2020
$1.4M
NIEHS NIH HHS P30 ES013508NIEHS NIH HHS R01 ES026903NIH HHS R01 ES011261NIH HHS R01 ES014575NIH HHS R01 ES016443NIH HHS R01 ES020349NIH HHS R01 ES024381NIH HHS R01 ES026903,
6 · The paper itself

Abstract

Linear regression is often used to estimate associations between chemical exposures and neurodevelopment at the mean of the outcome. However, the potential effect of chemicals may be greater among individuals at the 'tails' of outcome distributions. Here, we investigated distributional effects on the associations between gestational phthalate exposure and child Autism Spectrum Disorder (ASD)-related behaviors using quantile regression. We harmonized data from the Early Autism Risk Longitudinal Investigation (EARLI) (

Indexed as

Autism Spectrum DisorderAutistic DisorderEnvironmental PollutantsPhthalic AcidsChildChild, PreschoolCohort StudiesEnvironmental ExposureFemaleHumansPregnancyEnvironmental Pollutantsphthalic acidPhthalic Acidsendocrine-disrupting chemicalsneurodevelopmentphthalatesprenatal

Identifiers

PMID33573264
PMCPMC7908417

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.