Evidence map›Paper›PMID 33573230›Full record

ArticleBiology2021

Knockout of

Raquel Atienzar-Aroca, José-Daniel Aroca-Aguilar, Susana Alexandre-Moreno, Jesús-José Ferre-Fernández, Juan-Manuel Bonet-Fernández, María-José Cabañero-Varela, Julio Escribano

Open access · goldAbstract read
In one paragraph

Article in Biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Cannabidiol and the Canonical WNT/β-Catenin Pathway in Glaucoma.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Raquel Atienzar-ArocaÁrea de Genética, Facultad de Medicina de Albacete/Instituto de Investigación en Discapacidades Neurológicas (IDINE), Universidad de Castilla-La Mancha, 02006 Albacete, Spain.
José-Daniel Aroca-AguilarÁrea de Genética, Facultad de Medicina de Albacete/Instituto de Investigación en Discapacidades Neurológicas (IDINE), Universidad de Castilla-La Mancha, 02006 Albacete, Spain.ORCID 0000-0001-6487-1612
Susana Alexandre-MorenoÁrea de Genética, Facultad de Medicina de Albacete/Instituto de Investigación en Discapacidades Neurológicas (IDINE), Universidad de Castilla-La Mancha, 02006 Albacete, Spain.
Jesús-José Ferre-FernándezÁrea de Genética, Facultad de Medicina de Albacete/Instituto de Investigación en Discapacidades Neurológicas (IDINE), Universidad de Castilla-La Mancha, 02006 Albacete, Spain.ORCID 0000-0002-9511-2894
Juan-Manuel Bonet-FernándezÁrea de Genética, Facultad de Medicina de Albacete/Instituto de Investigación en Discapacidades Neurológicas (IDINE), Universidad de Castilla-La Mancha, 02006 Albacete, Spain.ORCID 0000-0002-8658-1592
María-José Cabañero-VarelaÁrea de Genética, Facultad de Medicina de Albacete/Instituto de Investigación en Discapacidades Neurológicas (IDINE), Universidad de Castilla-La Mancha, 02006 Albacete, Spain.
Julio EscribanoÁrea de Genética, Facultad de Medicina de Albacete/Instituto de Investigación en Discapacidades Neurológicas (IDINE), Universidad de Castilla-La Mancha, 02006 Albacete, Spain.ORCID 0000-0002-8919-8134
Instituto de Salud Carlos III · ES

Funding

Instituto de Salud Carlos III/European Regional Development Fund (ERDF) PI15/01193, PI19/00208 and RD16/0008/0019, OFTAREDRegional Ministry of Science and Technology of the Board of the Communities of "Castilla-La Mancha" SBPLY/17/180501/000404; http://www.educa.jccm.es/idiuniv/esUniversidad de Castilla-La Mancha 2019-GRIN-26945
6 · The paper itself

Abstract

Myocilin is a secreted glycoprotein with a poorly understood biological function and it is mainly known as the first glaucoma gene. To explore the normal role of this protein in vivo we developed a

Indexed as

myocmyocilinWntzebrafish sex determination

Identifiers

PMID33573230
PMCPMC7912607
OpenAlexW3128884169

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.