Evidence map›Paper›PMID 33573215›Full record

ArticleInternational journal of molecular sciences2021

Trichostatin A-Assisted Epigenomic Modulation Affects the Expression Profiles of Not Only Recombinant Human α1,2-Fucosyltransferase and α-Galactosidase A Enzymes But Also Galα1→3Gal Epitopes in Porcine Bi-Transgenic Adult Cutaneous Fibroblast Cells.

Jerzy Wiater, Marcin Samiec, Maria Skrzyszowska, Daniel Lipiński

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 30 citations in OpenAlex.

  1. Immunometabolism of Liver Xenotransplantation and Prospective Solutions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  2. Article
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  5. Zoological research · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Jerzy WiaterDepartment of Histology, Jagiellonian University Medical College, Kopernika 7 Street, 31-034 Kraków, Poland.ORCID 0000-0003-0911-3696
Marcin SamiecDepartment of Reproductive Biotechnology and Cryoconservation, National Research Institute of Animal Production, Krakowska 1 Street, 32-083 Balice n. Kraków, Poland.ORCID 0000-0002-4060-1893
Maria SkrzyszowskaDepartment of Reproductive Biotechnology and Cryoconservation, National Research Institute of Animal Production, Krakowska 1 Street, 32-083 Balice n. Kraków, Poland.ORCID 0000-0002-0068-6407
Daniel LipińskiDepartment of Biochemistry and Biotechnology, Poznań University of Life Sciences, Dojazd 11 Street, 60-647 Poznań, Poland.ORCID 0000-0002-0199-9245
National Research Institute of Animal Production · PLJagiellonian University · PLUniversity of Life Sciences in Poznań · PL

Funding

Ministry of Science and Higher Education in Poland 04-19-05-00
6 · The paper itself

Abstract

This study was conducted to explore whether trichostatin A-assisted epigenomic modulation (TSA-EM) can affect the expression of not only recombinant human α1,2-fucosyltransferase (rhα1,2-FT) and α-galactosidase A (rhα-Gal A) immune system enzymes but also Galα1→3Gal epitopes in ex vivo proliferating adult cutaneous fibroblast cells (ACFCs) derived from h

Indexed as

alpha-GalactosidaseAnimalsAnimals, Genetically ModifiedCell LineCloning, OrganismCryopreservationEmbryo, MammalianEpigenesis, GeneticEpitopesFibroblastsFucosyltransferasesGalactoside 2-alpha-L-fucosyltransferaseGene Knockout TechniquesGraft RejectionHumansHydroxamic Acidsalpha-GalactosidaseEpitopesFucosyltransferasesGalactoside 2-alpha-L-fucosyltransferaseGLA protein, humanHydroxamic AcidsRecombinant Proteinstrichostatin Aadult cutaneous fibroblast cellsbi-transgenicGalα1→3Gal epitopein vitro culturepigTSA-mediated epigenomic modulationxenotransplantationα1,2-fucosyltransferaseα-galactosidase A

Identifiers

PMID33573215
PMCPMC7866526
OpenAlexW3127978946

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.