ArticleJournal of clinical medicine2021
Nocturnal Hypoxemia and CT Determined Pulmonary Artery Enlargement in Smokers.
Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 6 citations in OpenAlex.
- Computed tomography-derived cardiac parameters versus biochemical inflammatory indices for discriminating disease severity and identifying cardiovascular comorbidity in obstructive sleep apnoea: A cross-sectional study.Sleep & breathing = Schlaf & Atmung · 2026Article
- REM-related obstructive sleep apnea: low AHI-high hypoxemia paradox.Sleep & breathing = Schlaf & Atmung · 2025Article
- Association of sleep disturbance and sleep apnea with the size of the thoracic aorta and the main pulmonary artery.Scientific reports · 2025Article
- Immune checkpoint inhibitor-related pneumonitis: research advances in prediction and management.Frontiers in immunology · 2024Review
- Association of Prolonged Nocturnal Hypoxemia with Clinical Worsening in Patients with Chronic Thromboembolic Pulmonary Hypertension Undergoing Pulmonary Endarterectomy.Reviews in cardiovascular medicine · 2023Article
- Prevalence of reduced lung diffusing capacity and CT scan findings in smokers without airflow limitation: a population-based study.BMJ open respiratory research · 2023Article
Corrections and comments
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Authors and funding
15 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPulmonary artery enlargement (PAE) detected using chest computed tomography (CT) is associated with poor outcomes in chronic obstructive pulmonary disease (COPD). It is unknown whether nocturnal hypoxemia occurring in smokers, with or without COPD, obstructive sleep apnoea (OSA) or their overlap, may be associated with PAE assessed by chest CT.
methodsWe analysed data from two prospective cohort studies that enrolled 284 smokers in lung cancer screening programs and completing baseline home sleep studies and chest CT scans. Main pulmonary artery diameter (PAD) and the ratio of the PAD to that of the aorta (PA:Ao ratio) were measured. PAE was defined as a PAD ≥ 29 mm in men and ≥27 mm in women or as a PA:Ao ratio > 0.9. We evaluated the association of PAE with baseline characteristics using multivariate logistic models.
resultsPAE prevalence was 27% as defined by PAD measurements and 11.6% by the PA:Ao ratio. A body mass index ≥ 30 kg/m
conclusionsIn smokers with or without COPD, nocturnal hypoxemia was associated with PAE independently of OSA coexistence.
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