Evidence map›Paper›PMID 33573186›Full record

ArticleGenes2021

Ablation of

Mi-Jin An, Geun-Seup Shin, Hyun-Min Lee, Jung-Woong Kim

Open access · goldAbstract read
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mi-Jin AnDepartment of Life Science, Chung-Ang University, Seoul 06974, Korea.ORCID 0000-0002-7588-6243
Geun-Seup ShinDepartment of Life Science, Chung-Ang University, Seoul 06974, Korea.
Hyun-Min LeeDepartment of Life Science, Chung-Ang University, Seoul 06974, Korea.ORCID 0000-0002-7970-2050
Jung-Woong KimDepartment of Life Science, Chung-Ang University, Seoul 06974, Korea.
Chung-Ang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Uracil is an unavoidable aberrant base in DNA sequences, the repair of which takes place by a highly efficient base excision repair mechanism. The removal of uracil from the genome requires multiple biochemical steps with conformational changes of DNA that inhibit DNA replication and interfere with transcription. However, the relevance of uracil in DNA for cellular physiology and transcriptional regulation is not fully understood. We investigated the functional roles of

Indexed as

ApoptosisCarcinoma, HepatocellularCell ProliferationCell SurvivalDNA DamageDNA RepairDNA ReplicationGene Expression Regulation, NeoplasticGene Knockdown TechniquesGene Knockout TechniquesHep G2 CellsHumansLiver NeoplasmsUracilUracil-DNA GlycosidaseSMUG1 protein, humanUracilUracil-DNA GlycosidaseDNA damage repairknock-outproliferationRNA-seqSMUG1

Identifiers

PMID33573186
PMCPMC7911780
OpenAlexW3128438429

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.