Evidence map›Paper›PMID 33573146›Full record

ReviewMedical sciences (Basel, Switzerland)2021

Epidemiology of Non-Hodgkin's Lymphoma.

Krishna C Thandra, Adam Barsouk, Kalyan Saginala, Sandeep Anand Padala, Alexander Barsouk, Prashanth Rawla

Open access · goldAbstract readReview
In one paragraph

Review in Medical sciences (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 225 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
225citing papers in PubMed, 2 pooled it
40.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

225 citing papers in PubMed, 2 syntheses or guidelines pooled it, 362 citations in OpenAlex.

  1. Pooled it
  2. The Role of [Tomography (Ann Arbor, Mich.) · 2024
    Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Glofitamab in Relapsed/Refractory Mantle Cell Lymphoma: Results From a Phase I/II Study.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2025
    Trial
  7. Trial
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. A proimmunotoxin nanodrug targeting AIDS-associated non-Hodgkin lymphoma.Journal of controlled release : official journal of the Controlled Release Society · 2026
    Article
  20. Article

165 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Krishna C ThandraDepartment of Pulmonary and Critical Care Medicine, Sentara Virginia Beach General Hospital, Virginia Beach, VA 23455, USA.
Adam BarsoukSidney Kimmel Cancer Center, Jefferson University, Philadelphia, PA 19107, USA.
Kalyan SaginalaPlains Regional Medical Group Internal Medicine, Clovis, NM 88101, USA.
Sandeep Anand PadalaDepartment of Medicine, Nephrology, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.ORCID 0000-0002-8773-073X
Alexander BarsoukHematologist-Oncologist, Allegheny Health Network, Pittsburgh, PA 15212, USA.
Prashanth RawlaDepartment of Medicine, Sovah Health, Martinsville, VA 24112, USA.ORCID 0000-0002-4361-8498
Allegheny Health Network · USAugusta University · USSentara Virginia Beach General Hospital · USSovah Health Martinsville · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-Hodgins's lymphoma (NHL) is the most common hematological malignancy worldwide, accounting for nearly 3% of cancer diagnoses and deaths. NHL is the seventh most prevalent cancer and has the sixth highest mortality among cancers in the US. NHL accounts for 4% of US cancer diagnoses, and incidence has increased 168% since 1975 (while survival has improved 158%). NHL is more common among men, those >65 years old, and those with autoimmune disease or a family history of hematological malignancies. NHL is a heterogenous disease, with each subtype associated with different risk factors. Marginal zone lymphoma (MZL) is strongly associated with Sjogren's syndrome (SS) and Hashimoto's thyroiditis, while peripheral T-cell lymphoma (PTCL) is most associated with celiac disease. Occupational exposures among farm workers or painters increases the risk of most of the common subtypes. Prior radiation treatment, obesity, and smoking are most highly associated with diffuse large B-cell lymphoma (DLBCL), while breast implants have been rarely associated with anaplastic large cell lymphoma (ALCL). Infection with Epstein-Barr Virus (EBV) is strongly associated with endemic Burkitts lymphoma. HIV and human herpes virus 8 (HHV-8), is predisposed to several subtypes of DLBCL, and human T-cell lymphoma virus (HTLV-1) is a causative agent of T-cell lymphomas. Obesity and vitamin D deficiency worsen NHL survival. Atopic diseases and alcohol consumption seem to be protective against NHL.

Indexed as

AgedEpstein-Barr Virus InfectionsFemaleHerpesvirus 4, HumanHumansLymphoma, B-Cell, Marginal ZoneLymphoma, Large B-Cell, DiffuseLymphoma, Non-HodgkinLymphoma, T-CellMaleObesityepidemiologyincidencemortalityNHLnon-Hodgkin’s lymphomaprevalencepreventionrisk factors

Identifiers

PMID33573146
PMCPMC7930980
OpenAlexW3126684855

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.