Evidence map›Paper›PMID 33573040›Full record

ArticleMolecules (Basel, Switzerland)2021

New 1,2,3-Triazole-Containing Hybrids as Antitumor Candidates: Design, Click Reaction Synthesis, DFT Calculations, and Molecular Docking Study.

Islam H El Azab, Hamdy S El-Sheshtawy, Rania B Bakr, Nadia A A Elkanzi

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Unlocking the medicinal arsenal ofHealth science reports · 2024
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Indian Shot (Journal of inflammation research · 2024
    Article
  16. Article
  17. Article
  18. Chemical and Pharmacological Profiling ofMolecules (Basel, Switzerland) · 2022
    Article
  19. Review
  20. Quantum Computational Investigation of (Molecules (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Islam H El AzabChemistry Department, College of Science, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.ORCID 0000-0003-1548-1102
Hamdy S El-SheshtawyChemistry Department, Faculty of Science, Kafrelsheikh University, Kafr ElSheikh 33516, Egypt.
Rania B BakrDepartment of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, P.O. Box 2014 Sakaka, Saudi Arabia.
Nadia A A ElkanziChemistry Department, Faculty of Science, Aswan University, P.O. Box 81528 Aswan, Egypt.ORCID 0000-0002-1687-1834

Funding

Taif University TURSP-2020/27
6 · The paper itself

Abstract

In an effort to improve and achieve biologically active anticancer agents, a novel series of 1,2,3-triazole-containing hybrids were designed and efficiently synthesized

Indexed as

Antineoplastic AgentsCell ProliferationClick ChemistryCycloaddition ReactionDensity Functional TheoryErbB ReceptorsGene Expression Regulation, NeoplasticHep G2 CellsHumansMolecular Docking SimulationNeoplasmsStructure-Activity RelationshipTriazolesAntineoplastic AgentsEGFR protein, humanErbB ReceptorsTriazoles1,2,3-triazoleantitumor activityclick chemistrycycloaddition reactionDFT calculationmolecular dockingpyrazole

Identifiers

PMID33573040
PMCPMC7866392

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.