Evidence map›Paper›PMID 33572982›Full record

ReviewInternational journal of molecular sciences2021

Cellular and Molecular Players in the Interplay between Adipose Tissue and Breast Cancer.

Francesca Reggiani, Paolo Falvo, Francesco Bertolini

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Francesca ReggianiTranslational Research Unit, Azienda USL- IRCCS di Reggio Emilia, 42123 Reggio Emilia, Italy.ORCID 0000-0002-4090-8908
Paolo FalvoLaboratory of Hematology-Oncology, European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0001-5743-5046
Francesco BertoliniLaboratory of Hematology-Oncology, European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0001-5660-3255

Funding

Associazione Italiana per la Ricerca sul Cancro IG20109
6 · The paper itself

Abstract

The incidence and severity of obesity are rising in most of the world. In addition to metabolic disorders, obesity is associated with an increase in the incidence and severity of a variety of types of cancer, including breast cancer (BC). The bidirectional interaction between BC and adipose cells has been deeply investigated, although the molecular and cellular players involved in these mechanisms are far from being fully elucidated. Here, we review the current knowledge on these interactions and describe how preclinical research might be used to clarify the effects of obesity over BC progression and morbidity, with particular attention paid to promising therapeutic interventions.

Indexed as

Adipose TissueAnimalsBreast NeoplasmsDisease Models, AnimalDisease ProgressionFemaleHumansInflammationObesityTumor Microenvironmentadipose tissuebreast cancerobesitypreclinical modelstumor microenvironment

Identifiers

PMID33572982
PMCPMC7866411

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.