Evidence map›Paper›PMID 33572948›Full record

ReviewPharmaceuticals (Basel, Switzerland)2021

The Role of Imaging in Planning Treatment for Central Serous Chorioretinopathy.

Stefano Da Pozzo, Pierluigi Iacono, Alessandro Arrigo, Maurizio Battaglia Parodi

Abstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Stefano Da PozzoTS Retina, 34170 Trieste, Italy.
Pierluigi IaconoIRCCS-Fondazione Bietti, 00198 Rome, Italy.ORCID 0000-0003-4562-539X
Alessandro ArrigoOphthalmology Department, San Raffaele University Hospital, 20132 Milan, Italy.ORCID 0000-0003-4715-8414
Maurizio Battaglia ParodiTS Retina, 34170 Trieste, Italy.ORCID 0000-0002-0385-7961

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Central serous chorioretinopathy (CSC) is a controversial disease both in terms of clinical classification and choice of therapeutic strategy. Choroidal layers, retinal pigment epithelium (RPE), photoreceptors, and retina are involved to varying degrees. Beyond well-known symptoms raising the clinical suspect of CSC and slit-lamp fundus examination, multimodal imaging plays a key role in assessing the extent of chorioretinal structural involvement. Subretinal fluid (SRF) originating from the choroid leaks through one or multiple RPE defects and spreads into the subretinal space. Spontaneous fluid reabsorption is quite common, but in some eyes, resolution can be obtained only after treatment. Multiple therapeutic strategies are available, and extensive research identified the most effective procedures. Imaging has carved a significant role in guiding the choice of the most appropriate strategy for each single CSC eye. Multiple biomarkers have been identified, and all of them represent a diagnostic and prognostic reference point. This review aims to provide an updated and comprehensive analysis of the current scientific knowledge about the role of imaging in planning the treatment in eyes affected by CSC.

Indexed as

central serous chorioretinopathyfluorescein angiographyfundus autofluorescenceindocyanine green angiographyoptical coherence tomography

Identifiers

PMID33572948
PMCPMC7912149

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.