Evidence map›Paper›PMID 33572768›Full record

ArticleGenes2021

TLR-Mediated Cytokine Gene Expression in Chicken Peripheral Blood Mononuclear Cells as a Measure to Characterize Immunobiotics.

Anna Slawinska, Aleksandra Dunislawska, Arkadiusz Plowiec, José Gonçalves, Maria Siwek

Open access · goldAbstract read
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Frontiers in immunology · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Chicken Immune Cell Assay to Model Adaptive Immune Responses In Vitro.Animals : an open access journal from MDPI · 2021
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Anna SlawinskaDepartment of Animal Biotechnology and Genetics, UTP University of Science and Technology, 85-084 Bydgoszcz, Poland.
Aleksandra DunislawskaDepartment of Animal Biotechnology and Genetics, UTP University of Science and Technology, 85-084 Bydgoszcz, Poland.ORCID 0000-0001-6608-0013
Arkadiusz PlowiecDepartment of Animal Biotechnology and Genetics, UTP University of Science and Technology, 85-084 Bydgoszcz, Poland.
José GonçalvesDepartment of Animal Biotechnology and Genetics, UTP University of Science and Technology, 85-084 Bydgoszcz, Poland.
Maria SiwekDepartment of Animal Biotechnology and Genetics, UTP University of Science and Technology, 85-084 Bydgoszcz, Poland.ORCID 0000-0003-4148-5174
Bydgoszcz University of Science and Technology · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunobiotics are probiotics that promote intestinal health by modulating immune responses. Immunobiotics are recognized by Toll-like receptors (TLRs) and activate cytokine gene expression. This study aimed to characterize cytokine gene expression in the chicken peripheral blood mononuclear cells (PBMC) stimulated with purified TLR ligands and live probiotics. PBMC were isolated from the whole blood. PBMC were stimulated with: lipopolysaccharide (LPS), CpG ODN, Pam3CSK4, Zymosan, galactooligosaccharides (GOS),

Indexed as

AnimalsChickensCytokinesGene Expression RegulationLeukocytesLeukocytes, MononuclearLipopeptidesLipopolysaccharidesOligosaccharidesProbioticsSaccharomyces cerevisiaeTh1 CellsToll-Like ReceptorsZymosanCytokinesLipopeptidesLipopolysaccharidesOligosaccharidesPam(3)CSK(4) peptideToll-Like ReceptorsZymosanGalactooligosaccharidesLactococcus lactispro-inflammatorySaccharomyces cerevisiaeTh1/Th2 immune responses

Identifiers

PMID33572768
PMCPMC7912573
OpenAlexW3128508143

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.